CAJ | 학술논문

目的分析高龄住院患者慢性便秘的临床特点、影响因素和用药情况.方法对2012年1-3月上海华东医院162例年龄≥85岁的住院老年患者进行问卷调查,其中男137例,女25例,筛选出符合罗马Ⅲ标准的慢性便秘患者112例,调查患者一般状况、便秘的相关影响因素、症状谱、伴随症状、既往用药情况、入院后用药情况共6大项目,采用非条件Logistic回归方法进行相关因素的统计学分析.结果 162例高龄患者平均年龄为(90±4)岁,慢性便秘的总患病率为69.1％(112/162)；Logistic回归分析显示活动少(OR=10.873)和饮食(OR=4.752)是其重要的影响因素.症状以排便费力最为常见,共85例(75.9％)；共有88例(78.6％)患者采用单独使用乳果糖或乳果糖与其他通便药合用的方式通便.使用乳果糖的原因主要是饮食限制31例(35.2％),预防误吸21例(23.9％)和其他通便药效果不佳36例(40.9％).结论高龄住院患者便秘患病率高,活动少和饮食为其主要影响因素,乳果糖应作为便秘治疗的一线用药.
목적 분석고령주원환자만성편비적림상특점、영향인소화용약정황.방법 대2012년1-3월상해화동의원162례년령≥85세적주원노년환자진행문권조사,기중남137례,녀25례,사선출부합라마Ⅲ표준적만성편비환자112례,조사환자일반상황、편비적상관영향인소、증상보、반수증상、기왕용약정황、입원후용약정황공6대항목,채용비조건Logistic회귀방법진행상관인소적통계학분석.결과 162례고령환자평균년령위(90±4)세,만성편비적총환병솔위69.1％(112/162)；Logistic회귀분석현시활동소(OR=10.873)화음식(OR=4.752)시기중요적영향인소.증상이배편비력최위상견,공85례(75.9％)；공유88례(78.6％)환자채용단독사용유과당혹유과당여기타통편약합용적방식통편.사용유과당적원인주요시음식한제31례(35.2％),예방오흡21례(23.9％)화기타통편약효과불가36례(40.9％).결론 고령주원환자편비환병솔고,활동소화음식위기주요영향인소,유과당응작위편비치료적일선용약.
Objective To analyze the clinical features,risk factors and drug uses of senior hospitalized patients with chronic constipation.Methods A total of 162 hospitalized patients aged 85 years and over at our hospital during the period of January-March 2012 conducted a questionnaire survey.There were 137 males and 25 females.And 112 cases of chronic constipation were diagnosed in accordance with the Rome Ⅲ criteria.The survey included general condition,risk factors of constipation,spectrum of symptoms,associated symptoms,previous medication and medication for constipation after admission.The results were statistically analyzed by Logistic regression.Results Their average age was (90 ± 4) years old.And the total prevalence of chronic constipation was 69.1％ (112/162).Logistic regression analysis showed that less activity (OR =10.873) and diet (OR =4.752) were the important risk factors.Defecation effort was the most common symptom (n =85,75.9％).A total of 88 cases (78.6％) took lactulose alone or lactulose plus other laxatives.The reasons of using lactulose were as follows:dietary restrictions (n =31,35.2％),aspiration prevention (n =21,23.9％) and poor efficacy of other laxatives (n =36,40.9％).Conclusions Prevalence of constipation is high among senior hospitalized patients.Less activity and diet are the main risk factors.And lactulose should be a first-line therapy.