CAJ | 학술논문

目的探讨手术联合125I密封籽源植入治疗唾液腺恶性肿瘤的效果.方法 2006年6月至2011年6月,解放军总医院口腔颌面外科105例唾液腺恶性肿瘤患者,联合手术在术中、术后将125I密封籽源植入到切除后瘤床内,通过影像学检查观察疗效及其并发症的回顾性研究.结果本组105例患者随访观察12～60个月者92例,其中无变化者占8.7％(8/92),近期有效率(CRPR)高达91.3％ (84/92).并发症主要为疼痛、黏膜溃疡,皮肤发黑,放射性骨髓炎.结论手术联合125I密封籽源植入治疗唾液腺恶性肿瘤是一种有效、方便而且不良反应小的治疗方法.
목적 탐토수술연합125I밀봉자원식입치료타액선악성종류적효과.방법 2006년6월지2011년6월,해방군총의원구강합면외과105례타액선악성종류환자,연합수술재술중、술후장125I밀봉자원식입도절제후류상내,통과영상학검사관찰료효급기병발증적회고성연구.결과 본조105례환자수방관찰12～60개월자92례,기중무변화자점8.7％(8/92),근기유효솔(CRPR)고체91.3％ (84/92).병발증주요위동통、점막궤양,피부발흑,방사성골수염.결론 수술연합125I밀봉자원식입치료타액선악성종류시일충유효、방편이차불량반응소적치료방법.
Objective To evaluate the efficacy and safety of brachytherapy plus operation for salivary gland malignant tumors.Methods From June 2006 to June 2011,a total of 105 patients with salivary gland malignant tumors undergone brachytherapy by implantation of iodine 125 seeds.The effectiveness was evaluated by periodical radiological film and computed tomography.The complications were analyzed.Results Among them,92 patients were observed for 12-60 months.The rates of clinical response rate (CRPR) and no change (NC) were 91.3％(84/92) and 8.7％ (8/92) respectlvely of the patients.Pain,mucosa ulcer,skin darkness and radiation osteomyelitis were common complications.Conclusion The combined regimen of operation and brachytherapy of iodine 125 seed implantation for salivary gland malignant tumors is quite effective and convenient.And it has fewer complications.