CAJ | 학술논문

目的探讨脑胶质瘤瘤周水肿程度与患者一般情况及病情、病理之间的关系.方法对2010至2011年浙江省宁波市医疗中心李惠利医院69例手术后经病理证实为胶质瘤的患者进行分析,对可能促进瘤周水肿形成的性别、年龄、KPS评分、发病至就诊时间及肿瘤大小、部位、形状、病理分级进行逐步多元线性回归分析.结果 69例均发生瘤周水肿,进入水肿指数回归方程的相关因素有肿瘤病理分级、发病至就诊时间、术前KPS分级及年龄,其偏回归系数依次为0.853、0.456、-0.352和0.291(P＜0.01).结论脑胶质瘤瘤周水肿程度与患者病理分级、发病至就诊时间、术前KPS评分及年龄有关,与性别、肿瘤大小、肿瘤部位及形状无关.
목적 탐토뇌효질류류주수종정도여환자일반정황급병정、병리지간적관계.방법 대2010지2011년절강성저파시의료중심리혜리의원69례수술후경병리증실위효질류적환자진행분석,대가능촉진류주수종형성적성별、년령、KPS평분、발병지취진시간급종류대소、부위、형상、병리분급진행축보다원선성회귀분석.결과 69례균발생류주수종,진입수종지수회귀방정적상관인소유종류병리분급、발병지취진시간、술전KPS분급급년령,기편회귀계수의차위0.853、0.456、-0.352화0.291(P＜0.01).결론 뇌효질류류주수종정도여환자병리분급、발병지취진시간、술전KPS평분급년령유관,여성별、종류대소、종류부위급형상무관.
Objective To explore the correlation of various influencing factors with the extent of peritumoral brain glioma edema.Methods A total of 69 glioma cases were confirmed by pathology after operation.And stepwise multiple linear regression analysis was performed on gender,age,Karnofsky performance scale (KPS) score,onset to treatment time,tumor size,location,shape and WHO pathological grade.Results All of them had peritumoral edema.The relevant factors included pathology grading,onset to treatment time,KPS score and age.The data were entered into the regression equation of edema index.The partial regression coefficients were 0.853,0.456,-0.352 and 0.291 respectively (P ＜ 0.01).Conclusion Peritumoral brain edema in glioma patients are correlated with WHO pathologic grading,onset to treatment time,KPS score and age.But it has no correlation with patient gender,tumor location,tumor size and shape.