中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2013年
5期
348-351
,共4页
脑缺血%卒中%预后%危险因素%脑血管循环%差异
腦缺血%卒中%預後%危險因素%腦血管循環%差異
뇌결혈%졸중%예후%위험인소%뇌혈관순배%차이
Brain ischemic%Stroke%Prognosis%Risk factors%Cerebral vascular circulation%Disparity
目的 探讨常见危险因素与中国北方青年前后循环缺血性脑卒中及其短期预后的关系,为临床的预防和治疗提供依据.方法 本研究人选中国北方青年缺血性脑卒中患者446例,均来自首都医科大学宣武医院神经科2001-2010年间住院患者,其中单纯前循环353例、非前循环93例；单纯后循环56例、非后循环390例；同时累及前后循环37例,非前后循环同时受累409例.用非条件Logistic回归方法分析确定预测前后循环病变发生及影响其短期预后的危险因素.结果 Logistic回归分析得出的预测因素包括:年龄增长、高白细胞计数增加非前循环病变发生风险(OR0.951,P =0.030;OR0.876,P=0.014)；饮酒史增加单纯后循环病变发生风险(OR1.856,P=0.047)；高NIHSS评分,高总胆固醇含量预示单纯前循环病变短期预后不良(OR 1.884,P=0.000;OR1.792,P=0.008).结论 年龄、白细胞计数、饮酒、NIHSS评分和总胆固醇与中国北方青年缺血性脑卒中前后循环不同部位病变的发生及短期预后不良密切相关.
目的 探討常見危險因素與中國北方青年前後循環缺血性腦卒中及其短期預後的關繫,為臨床的預防和治療提供依據.方法 本研究人選中國北方青年缺血性腦卒中患者446例,均來自首都醫科大學宣武醫院神經科2001-2010年間住院患者,其中單純前循環353例、非前循環93例；單純後循環56例、非後循環390例；同時纍及前後循環37例,非前後循環同時受纍409例.用非條件Logistic迴歸方法分析確定預測前後循環病變髮生及影響其短期預後的危險因素.結果 Logistic迴歸分析得齣的預測因素包括:年齡增長、高白細胞計數增加非前循環病變髮生風險(OR0.951,P =0.030;OR0.876,P=0.014)；飲酒史增加單純後循環病變髮生風險(OR1.856,P=0.047)；高NIHSS評分,高總膽固醇含量預示單純前循環病變短期預後不良(OR 1.884,P=0.000;OR1.792,P=0.008).結論 年齡、白細胞計數、飲酒、NIHSS評分和總膽固醇與中國北方青年缺血性腦卒中前後循環不同部位病變的髮生及短期預後不良密切相關.
목적 탐토상견위험인소여중국북방청년전후순배결혈성뇌졸중급기단기예후적관계,위림상적예방화치료제공의거.방법 본연구인선중국북방청년결혈성뇌졸중환자446례,균래자수도의과대학선무의원신경과2001-2010년간주원환자,기중단순전순배353례、비전순배93례；단순후순배56례、비후순배390례；동시루급전후순배37례,비전후순배동시수루409례.용비조건Logistic회귀방법분석학정예측전후순배병변발생급영향기단기예후적위험인소.결과 Logistic회귀분석득출적예측인소포괄:년령증장、고백세포계수증가비전순배병변발생풍험(OR0.951,P =0.030;OR0.876,P=0.014)；음주사증가단순후순배병변발생풍험(OR1.856,P=0.047)；고NIHSS평분,고총담고순함량예시단순전순배병변단기예후불량(OR 1.884,P=0.000;OR1.792,P=0.008).결론 년령、백세포계수、음주、NIHSS평분화총담고순여중국북방청년결혈성뇌졸중전후순배불동부위병변적발생급단기예후불량밀절상관.
Objective To explore different risk factors between anterior and posterior circulation affecting onset and prognosis in the North Chinese young ischemic stroke patients.Methods This study included 446 cases of young ischemic stroke patients in northern China.All patients were recruited from our department from 2001 to 2010,Among them,the lesion sites were anterior circulation infarction (n =353),posterior circulation infarction (n =56) and both anterior and posterior circulation infarction (n =37).Nonconditional Logistic regression analysis was used to determine the risk factors of predicting the onset of either anterior or posterior or mixed stroke and their short-term prognosis.Results Advanced age and a higher white blood cell count (WBC) increased the risk of non-anterior circulation lesions (OR 0.951,P =0.030 ;OR 0.876,P =0.014).Patients with a history of alcohol drinking had an increased risk for simple posterior circulation lesions (OR 1.856,P =0.047) ; Both high National Institute of Health stroke scale (NIHSS score) and high total cholesterol (TC) predicted a poor short-term prognosis for simple anterior circulation lesions(OR 1.884,P=0.000; OR 1.792,P=0.008).Conclusion Age,WBC count,alcohol intake,NIHSS score and TC are closely correlated with different lesions of northern Chinese young patients with ischemic stroke and their poor short-term prognosis.
