CAJ | 학술논문

目的探讨第三脑室脊索样胶质瘤的MRI表现特征.方法回顾性分析南京军区南京总医院2006至2011年经手术病理证实的5例第三脑室脊索样胶质瘤患者的MRI表现及病理学特点.结果 5例患者中男2例、女3例,年龄32～ 50岁(平均39岁),临床主要表现为头痛、头晕,女性常伴有月经不调.肿瘤均位于鞍上第三脑室前部,直径2 ～4 cm,境界清楚.T1WI呈等或稍低信号,T2WI呈高信号,DWI呈低信号.增强扫描瘤体显著强化,4例强化均匀,1例瘤体较大(直径约4 cm),可见囊变并呈不均匀强化.结论第三脑室脊索样胶质瘤是一种独特的、罕见的中枢神经系统肿瘤,MRI能显示该肿瘤的生长部位及形态,有助于其定位及定性诊断,但确诊仍需依靠病理学检查.
목적 탐토제삼뇌실척색양효질류적MRI표현특정.방법 회고성분석남경군구남경총의원2006지2011년경수술병리증실적5례제삼뇌실척색양효질류환자적MRI표현급병이학특점.결과 5례환자중남2례、녀3례,년령32～ 50세(평균39세),림상주요표현위두통、두훈,녀성상반유월경불조.종류균위우안상제삼뇌실전부,직경2 ～4 cm,경계청초.T1WI정등혹초저신호,T2WI정고신호,DWI정저신호.증강소묘류체현저강화,4례강화균균,1례류체교대(직경약4 cm),가견낭변병정불균균강화.결론 제삼뇌실척색양효질류시일충독특적、한견적중추신경계통종류,MRI능현시해종류적생장부위급형태,유조우기정위급정성진단,단학진잉수의고병이학검사.
Objective To study the features of chordoid glioma of the third ventricle.Methods The MRI findings of five cases of chordoid glioma of the third ventricle pathologically proved were reviewed and correlated with operative and pathologic reports.Results The patients were 3 women and 2 men,30-50 years old in age.The main symptoms were progressive headache,and usually erratic irregular menstruation in women.Five cases of chordoid glioma were located in the third ventricles.Grossly,the 5 tumors size range were 2-4 cm in diameter,and were well-circumscribed mass with rouded or irregular morphological features on standard MRI.They were isointense to slightly hypointense relative to normal white matter in T1WI,slightly hyperintense in T2WI and hypointense in DWI on MR.The significant contrast enhancement of this tumour on postcontrast T1WI result from a breakdown of the blood-brain barrier and extavasation of contrast medium,as confirmed by the absence of vascular proliferation on histological examination.4 tumors were enhanced equivalently and 1 tumor had central nonenhancing components representing small cysts,because of its large size (4 cm in diameter).Conclusions Chordoid glioma of the third ventricle is rare and the MR appearances possess unique features which are very helpful in diagnosis of chordoid glioma,but to make a definite diagnosis is based on clinical and histopathological features and immunohistochemical staining.