CAJ | 학술논문

目的比较周围静脉溶栓与深静脉置管溶栓治疗急性下肢深静脉血栓形成(DVT)的近期疗效与并发症,评价深静脉置管溶栓的应用价值.方法收集2008年1月至2010年12月中国医科大学附属第一医院放射科86例DVT患者,分为周围浅静脉溶栓组(A组,33例)和深静脉置管溶栓组(B组,53例),对比两组下肢消肿率、静脉通畅率及近期并发症的差异.结果两组消肿率比较(大腿A组59％±33％,B组66％±30％；小腿A组67％±31％,B组60％±30％),差异无统计学意义(P＞0.05).静脉通畅率比较,B组(57％±23％)优于A组(38％±26％),差异有统计学意义(P＜0.05).两组出血发生率差异无统计学意义(P＞0.05),均无症状性肺梗死发生.结论两种溶栓方法均可有效改善急性下肢DVT症状,深静脉置管溶栓静脉通畅率高,且不增加溶栓出血概率.
목적 비교주위정맥용전여심정맥치관용전치료급성하지심정맥혈전형성(DVT)적근기료효여병발증,평개심정맥치관용전적응용개치.방법 수집2008년1월지2010년12월중국의과대학부속제일의원방사과86례DVT환자,분위주위천정맥용전조(A조,33례)화심정맥치관용전조(B조,53례),대비량조하지소종솔、정맥통창솔급근기병발증적차이.결과 량조소종솔비교(대퇴A조59％±33％,B조66％±30％；소퇴A조67％±31％,B조60％±30％),차이무통계학의의(P＞0.05).정맥통창솔비교,B조(57％±23％)우우A조(38％±26％),차이유통계학의의(P＜0.05).량조출혈발생솔차이무통계학의의(P＞0.05),균무증상성폐경사발생.결론 량충용전방법균가유효개선급성하지DVT증상,심정맥치관용전정맥통창솔고,차불증가용전출혈개솔.
Objective To evaluate the effects of catheter-direct thrombolysis in acute deep venous thrombosis (DVT).Methods A total of 86 cases were divided into 2 groups of peripheral venous thrombolysis (group A,n =33) and catheter-direct thrombolysis (group B,n =53).The curative effect of two groups was compared by swelling rate and vascular potency.Results No significant difference existed in swelling rate between two groups (P ＞0.05).Vascular patency rates of group B was significantly better than those of group A (P ＜ 0.01).The incidence of bleeding had no significant difference (P ＞ 0.05) and there was no asymptomatic pulmonary embolism in two groups.Conclusion Both treatments of acute DVT are effective in improving symptoms.But catheter-directed thrombolysis results in significant vascular patency rate and does not increase the risk of thrombolytic bleeding.