中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2013年
8期
592-593
,共2页
同种抗体%MNSs血型系统%抗-Mia
同種抗體%MNSs血型繫統%抗-Mia
동충항체%MNSs혈형계통%항-Mia
Isoantibodies%MNSs blood-group system%anti-Mia
目的 评价MNS血型系统同种抗体在我国医疗机构住院患者中的发生频率与临床意义.方法 回顾性分析2009年8月至2012年7月复旦大学附属中山医院输血科检出的MNS血型系统同种抗体的特异性及临床特征.结果 66042例住院患者中检出187例同种不规则抗体(0.28％),其中MNS血型系统同种抗体70例(37.4％),按特异性依次为抗-M(34例,18.2％)、抗-Mia(34例,18.2％)、抗-S(2例,1.1％).抗-Mia多见于有输血史者(16/34比5/34,P＝0.004),并较易合并其他同种抗体.结论 MNS血型系统同种抗体临床检出率仅次于Rh血型系统,其中抗-Mia是我国南方人群中重要的输血相关抗体.
目的 評價MNS血型繫統同種抗體在我國醫療機構住院患者中的髮生頻率與臨床意義.方法 迴顧性分析2009年8月至2012年7月複旦大學附屬中山醫院輸血科檢齣的MNS血型繫統同種抗體的特異性及臨床特徵.結果 66042例住院患者中檢齣187例同種不規則抗體(0.28％),其中MNS血型繫統同種抗體70例(37.4％),按特異性依次為抗-M(34例,18.2％)、抗-Mia(34例,18.2％)、抗-S(2例,1.1％).抗-Mia多見于有輸血史者(16/34比5/34,P＝0.004),併較易閤併其他同種抗體.結論 MNS血型繫統同種抗體臨床檢齣率僅次于Rh血型繫統,其中抗-Mia是我國南方人群中重要的輸血相關抗體.
목적 평개MNS혈형계통동충항체재아국의료궤구주원환자중적발생빈솔여림상의의.방법 회고성분석2009년8월지2012년7월복단대학부속중산의원수혈과검출적MNS혈형계통동충항체적특이성급림상특정.결과 66042례주원환자중검출187례동충불규칙항체(0.28％),기중MNS혈형계통동충항체70례(37.4％),안특이성의차위항-M(34례,18.2％)、항-Mia(34례,18.2％)、항-S(2례,1.1％).항-Mia다견우유수혈사자(16/34비5/34,P＝0.004),병교역합병기타동충항체.결론 MNS혈형계통동충항체림상검출솔부차우Rh혈형계통,기중항-Mia시아국남방인군중중요적수혈상관항체.
Objective To explore the occurrence and clinical significance of erythrocyte alloantibodies to MNS blood group system among hospitalized patients in China.Methods The specificity and clinical features of erythrocyte allo-antibodies detected from August 2009 to July 2012 were retrospectively analyzed.Results A total of 187 erythrocyte allo-antibodies were detected from 66 042 hospitalized patients (0.28％) among which 70 (37.4％) were specific to MNS blood group system.Antibody frequencies were as follows:anti-M,18.2％ ; anti-Mia,18.2％ ; anti-S,1.1％.Anti-Mia was more frequent among transfused patients (16/34 vs 5/34,P =0.004),and tended to be accompanied by other allo-antibodies.Conclusions Antibodies to MNS blood group system are second only to Rh system as the most common erythrocyte allo-antibodies in China.And anti-Mia is an important transfusion-related allo-antibody among the patients of southern ancestry.
