CAJ | 학술논문

目的对异位妊娠期待治疗成功的因素进行回顾性分析.方法对山东大学齐鲁医院计划生育科2004年8月至2012年1月186例异位妊娠期待治疗病例进行回顾性分析,不需要手术或药物治疗为治愈组,需要手术或药物治疗的为失败组.结果 140例期待治疗成功,治愈率75.27％；治愈组与失败组包块大小经秩和检验,差异无统计学意义(P＞0.05)；两组包块有囊性结构患者例数差异有统计学意义(P＜0.05).两组初始血β-人绒毛膜促性腺激素(hCG)差异有统计学意义(P＜0.01),初始血β-hCG在ROC曲线上临界点为634 IU/L,第3～5天检测β-hCG与初始血β-hCG的比值在ROC曲线上临界点为0.711.结论初始血β-hCG≤634 IU/L或第3～5天检测血β-hCG下降为初始的0.711倍时,可期待治疗.包块有无囊性结构是影响期待治疗成功的因素.
목적 대이위임신기대치료성공적인소진행회고성분석.방법 대산동대학제로의원계화생육과2004년8월지2012년1월186례이위임신기대치료병례진행회고성분석,불수요수술혹약물치료위치유조,수요수술혹약물치료적위실패조.결과 140례기대치료성공,치유솔75.27％；치유조여실패조포괴대소경질화검험,차이무통계학의의(P＞0.05)；량조포괴유낭성결구환자례수차이유통계학의의(P＜0.05).량조초시혈β-인융모막촉성선격소(hCG)차이유통계학의의(P＜0.01),초시혈β-hCG재ROC곡선상림계점위634 IU/L,제3～5천검측β-hCG여초시혈β-hCG적비치재ROC곡선상림계점위0.711.결론 초시혈β-hCG≤634 IU/L혹제3～5천검측혈β-hCG하강위초시적0.711배시,가기대치료.포괴유무낭성결구시영향기대치료성공적인소.
Objective To analyze select patients of ectopic pregnancy for expectant management.Methods Retrospective analyses were conducted for the relative factors of 180 cases of ectopic pregnancy with expectant management at Department of Family Planning of our hospital from August 2004 to January 2012.Their general clinical data,clinical manifestations and laboratory tests were collected.The cases requiring neither surgery nor drug therapy belonged to the cure group while the rest fell into the failure group.Results A total of 140 patients were successfully managed with a cure rate of 75.27％.There was no significant difference between two groups in size of mass on ultrasonography (P ＞ 0.05).The cases with gestational sac of mass on ultrasonography had statistical difference between two groups (P ＜0.05).Statistical difference existed between two groups (P ＜ 0.01) in initial blood beta-human chorionic gonadotropin (β-hCG),initial bloodβ-hCG and D3-5/D0 (ratio of bloodβ-hCG at day 3-5 and initial)were the variables for predicting the likelihood of successful expectant management under the ROC curve.The Youden Index was the largest at an initial bloodβ-hCG of 634 IU/L or D3-5/D0 of 0.711.Conclusion At blood β-hCG≤634 IU/L or D3-5/D0 ＜ 0.711,expectant management may be offered.And mass with gestational sac on ultrasonography is a relative factor of expectant management.