CAJ | 학술논문

目的探讨甲状旁腺肿瘤的临床特征、诊断方法及治疗手段.方法回顾性分析2003年1月至2011年12月河南省肿瘤医院头颈科51例甲状旁腺肿瘤的临床资料,总结其临床表现、检查手段及手术方式.结果 51例患者中,腺瘤32例,囊肿18例,癌1例.颈部彩超的敏感度及阳性预测值为84.3％和93.5％,99Tcm-甲氧异腈(MIBI)甲状旁腺显影的敏感度及阳性预测值为91.7％和100.0％.32例甲状旁腺腺瘤和1例甲状旁腺癌有血钙和甲状旁腺素增高,术后均恢复正常,18例甲状旁腺囊肿甲状旁腺素和血钙无异常.结论甲状旁腺腺瘤表现复杂,甲状旁腺囊肿多表现为颈部肿物.血钙、甲状旁腺素和颈部彩超检查可作为其筛查手段,99Tcm-MIBI适于腺瘤定位.甲状旁腺肿瘤手术治疗疗效确切,术中即时检测甲状旁腺素能够确保手术彻底.
목적 탐토갑상방선종류적림상특정、진단방법급치료수단.방법 회고성분석2003년1월지2011년12월하남성종류의원두경과51례갑상방선종류적림상자료,총결기림상표현、검사수단급수술방식.결과 51례환자중,선류32례,낭종18례,암1례.경부채초적민감도급양성예측치위84.3％화93.5％,99Tcm-갑양이정(MIBI)갑상방선현영적민감도급양성예측치위91.7％화100.0％.32례갑상방선선류화1례갑상방선암유혈개화갑상방선소증고,술후균회복정상,18례갑상방선낭종갑상방선소화혈개무이상.결론 갑상방선선류표현복잡,갑상방선낭종다표현위경부종물.혈개、갑상방선소화경부채초검사가작위기사사수단,99Tcm-MIBI괄우선류정위.갑상방선종류수술치료료효학절,술중즉시검측갑상방선소능구학보수술철저.
Objective To explore the clinical features,diagnosis and surgical treatment of parathyroid neoplasms.Methods From January 2003 to December 2011,a total of 51 patients were recruited.Their clinical data,presentations,examinations and surgical approaches were analyzed retrospectively.Results Among them,there were parathyroid adenoma (n =32),parathyroid cysts (n =18) and parathyroid carcinoma (n =1).The sensitivity and positive rate of neck ultrasonography and 99Tcmmethoxyisobutylisonitrile (MIBI) were 84.3％ and 93.5％,91.7％ and 100.0％ respectively.The high levels of serum calcium and parathyroid hormone (PTH) in 32 cases of parathyroid adenoma and 1 case of parathyroid carcinoma returned to normal after operation.The levels of serum calcium and PTH remained normal in 18 cases of parathyroid cysts.Conclusions The clinical manifestations of parathyroid adenoma were complex.The serum levels of calcium and PTH and neck ultrasonography are preferred screening tools for parathyroid neoplasms.99Tcm-MIBI is suitable for tumor localization.Surgery is effective and safe for parathyroid neoplasm.Real time intraoperative monitoring of PTH is of great importance.