CAJ | 학술논문

不恰当的抗生素经验治疗以及延迟的抗生素针对性治疗与增高的临床死亡率高度相关.由于传统的微生物培养与鉴定技术依赖于病原微生物生长而耗时较长,临床常常采用经验性广谱抗生素治疗感染性疾病,这又进一步促进了耐药的发生.为了改变这一现状,临床微生物学实验室应尽可能提供早期快速病原学报告,以实现从针对性的起始抗感染治疗或经验治疗到针对性治疗的及时转换.临床微生物学实验室应整合各种微生物学快速检验技术,优化工作流程,建设快速反应型临床微生物学实验室.
불흡당적항생소경험치료이급연지적항생소침대성치료여증고적림상사망솔고도상관.유우전통적미생물배양여감정기술의뢰우병원미생물생장이모시교장,림상상상채용경험성엄보항생소치료감염성질병,저우진일보촉진료내약적발생.위료개변저일현상,림상미생물학실험실응진가능제공조기쾌속병원학보고,이실현종침대성적기시항감염치료혹경험치료도침대성치료적급시전환.림상미생물학실험실응정합각충미생물학쾌속검험기술,우화공작류정,건설쾌속반응형림상미생물학실험실.
Inadequate empirical antibiotic therapy and delayed target therapy have been demonstrated to be significantly associated with higher mortality.Because microbiological results based on the traditional culture and identification require quite a long time,empirical broad-spectrum antimicrobial therapy is often initiated according to the clinical presentation,which may resulting in the development of antimicrobial resistance.One of the strategies to alter the dilemma situation is that the initial empirical therapy is adjusted to definitive therapy as early as possible,which can only be done on the basis of rapid microbiological reports.Clinical microbiology laboratories should integrate a variety of rapid detection methods,improve working process,present reports as soon as possible,and bear fast-responsibility.