国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2014年
19期
2989-2991
,共3页
生长抑素%泮托拉唑%急性上消化道出血
生長抑素%泮託拉唑%急性上消化道齣血
생장억소%반탁랍서%급성상소화도출혈
Somatostatin%Pantoprazole%Acute upper gastrointestinal hemorrhage
目的 探讨生长抑素联合泮托拉唑治疗急性上消化道出血的临床效果.方法 将我科2011年3月至2013年9月收治的88例急性上消化道出血患者按不同治疗方法分为对照组(40例,常规治疗基础上加用泮托拉唑)和试验组(48例,泮托拉唑联合生长抑素治疗),对两组患者治疗效果进行综合比较.结果 (1)试验组治疗总有效率91.67％(44/48)明显高于对照组75.00％(30/40)(P＜0.05);(2)试验组PLT、PCT分别为(265.0±11.3) ×109/L、(25.5±5.2)％,对照组为(232.5±10.9)×109/L、(21.4±5.1)％,组间比较有统计学差异(P＜0.01);(3)试验组止血成功时间及住院时间分别为(30.3±10.2)h、(7.0±1.4)d,对照组为(46.5±10.9)h、(11.2±2.6)d,组间比较有统计学差异(P＜0.01).结论 生长抑素联合泮托拉唑治疗急性上消化道出血效果显著,值得临床推广应用.
目的 探討生長抑素聯閤泮託拉唑治療急性上消化道齣血的臨床效果.方法 將我科2011年3月至2013年9月收治的88例急性上消化道齣血患者按不同治療方法分為對照組(40例,常規治療基礎上加用泮託拉唑)和試驗組(48例,泮託拉唑聯閤生長抑素治療),對兩組患者治療效果進行綜閤比較.結果 (1)試驗組治療總有效率91.67％(44/48)明顯高于對照組75.00％(30/40)(P＜0.05);(2)試驗組PLT、PCT分彆為(265.0±11.3) ×109/L、(25.5±5.2)％,對照組為(232.5±10.9)×109/L、(21.4±5.1)％,組間比較有統計學差異(P＜0.01);(3)試驗組止血成功時間及住院時間分彆為(30.3±10.2)h、(7.0±1.4)d,對照組為(46.5±10.9)h、(11.2±2.6)d,組間比較有統計學差異(P＜0.01).結論 生長抑素聯閤泮託拉唑治療急性上消化道齣血效果顯著,值得臨床推廣應用.
목적 탐토생장억소연합반탁랍서치료급성상소화도출혈적림상효과.방법 장아과2011년3월지2013년9월수치적88례급성상소화도출혈환자안불동치료방법분위대조조(40례,상규치료기출상가용반탁랍서)화시험조(48례,반탁랍서연합생장억소치료),대량조환자치료효과진행종합비교.결과 (1)시험조치료총유효솔91.67％(44/48)명현고우대조조75.00％(30/40)(P＜0.05);(2)시험조PLT、PCT분별위(265.0±11.3) ×109/L、(25.5±5.2)％,대조조위(232.5±10.9)×109/L、(21.4±5.1)％,조간비교유통계학차이(P＜0.01);(3)시험조지혈성공시간급주원시간분별위(30.3±10.2)h、(7.0±1.4)d,대조조위(46.5±10.9)h、(11.2±2.6)d,조간비교유통계학차이(P＜0.01).결론 생장억소연합반탁랍서치료급성상소화도출혈효과현저,치득림상추엄응용.
Objective To investigate the clinical effect of somatostatin combined with pantoprazole in the treatment of acute upper gastrointestinal hemorrhage.Methods 88 cases of acute upper gastrointestinal hemorrhage in our hospital from March 2011 to September 2013 were divided into control group (40 cases,given pantoprazole on the basis of conventional) and experimental groap (48 cases,given somatostatin combined with pantoprazole),the efficacy of two groups were compared.Results ① The effective-rate of experimental group (91.67％) was higher than that of control group (75.00％) (P ＜ 0.05); ② After 3 days of treatment,PLT,PCT of experimental group were (265.0 ± 11.3) × 109/L,(25.5 ± 5.2)％,those were (232.5 ± 10.9) × 109/L,(21.4 ± 5.1)％ in control group,there were statistically significant differences between two groups (P ＜ 0.01); ③)The time of successful hemostasis and hospitalization of experimental group were (30.3 ± 10.2) h and (7.0 ± 1.4) d,those were (46.5 ± 10.9)h and (11.2 ± 2.6) d in control group,there were statistically significant differences between two groups (P ＜ 0.01).Conclusion Somatostatin combined with pantoprazole has significant effect in treating acute upper gastrointestinal hemorrhage,which is worthy of clinical promotion.
