中华检验医学杂志
中華檢驗醫學雜誌
중화검험의학잡지
CHINESE JOURNAL OF LABORATORY MEDICINE
2013年
12期
1074-1079
,共6页
乙型肝炎病毒%耐药%突变%检测
乙型肝炎病毒%耐藥%突變%檢測
을형간염병독%내약%돌변%검측
Hepatitis B virus%Resistance%Mutation%Detection
耐药突变是慢性乙型肝炎患者长期应用核苷(酸)类抗病毒药物治疗过程中难以避免的现象.早期耐药突变的检测对调整治疗方案、降低耐药发生率、提高疗效及实施个体化治疗具有显著意义.
耐藥突變是慢性乙型肝炎患者長期應用覈苷(痠)類抗病毒藥物治療過程中難以避免的現象.早期耐藥突變的檢測對調整治療方案、降低耐藥髮生率、提高療效及實施箇體化治療具有顯著意義.
내약돌변시만성을형간염환자장기응용핵감(산)류항병독약물치료과정중난이피면적현상.조기내약돌변적검측대조정치료방안、강저내약발생솔、제고료효급실시개체화치료구유현저의의.
Drug-resistance mutation is inevitable during long-term monotherapy with nucleus(t)ide analogues in hepatitis B patients.Early detection the drug-resistance mutations could contribute to adjusting the therapeutic regimen,reducing resistance rate,improving therapeutic efficacy and performing individual treatment.
