中华检验医学杂志
中華檢驗醫學雜誌
중화검험의학잡지
CHINESE JOURNAL OF LABORATORY MEDICINE
2014年
4期
256-260
,共5页
抗菌药%微生物敏感性试验%肠杆菌科
抗菌藥%微生物敏感性試驗%腸桿菌科
항균약%미생물민감성시험%장간균과
Anti-bacterial agents%Microbial sensitivity tests%Enterobacteriaceae
准确快速的病原菌诊断,同时报告正确的药敏结果,是实现感染性疾患个体化治疗的前提.美国临床和实验室标准协会(CLSI)每年修订的折点引起临床工作者的广泛关注.本文介绍了CLSI M100-S24的更新内容.CLSI 2014年文件最大改变之处是修改了肠杆菌科细菌头孢吡肟的药敏折点,并引入“剂量依赖性敏感”的概念.正确理解和运用新折点,对优化药物使用具有重要意义.
準確快速的病原菌診斷,同時報告正確的藥敏結果,是實現感染性疾患箇體化治療的前提.美國臨床和實驗室標準協會(CLSI)每年脩訂的摺點引起臨床工作者的廣汎關註.本文介紹瞭CLSI M100-S24的更新內容.CLSI 2014年文件最大改變之處是脩改瞭腸桿菌科細菌頭孢吡肟的藥敏摺點,併引入“劑量依賴性敏感”的概唸.正確理解和運用新摺點,對優化藥物使用具有重要意義.
준학쾌속적병원균진단,동시보고정학적약민결과,시실현감염성질환개체화치료적전제.미국림상화실험실표준협회(CLSI)매년수정적절점인기림상공작자적엄범관주.본문개소료CLSI M100-S24적경신내용.CLSI 2014년문건최대개변지처시수개료장간균과세균두포필우적약민절점,병인입“제량의뢰성민감”적개념.정학리해화운용신절점,대우화약물사용구유중요의의.
Individualized therapy is dependent on rapid and accurate diagnosis of pathogens,and refined susceptibility reporting.The annually revised interpretive criteria of Clinical and Laboratory Standards Institute (CLSI) causes widespread concern of microbiologists.The major changes in CLSI M100-S24 are described in this article.The document mainly changed the Cefepime breakpoint for Enterobacteriaceae and introduced a new concept--" susceptible-dose dependent" interpretive category.Optimizing the use of antimicrobial agents requires clinical microbiologists and clinicians to have a good knowledge of the new breakpoints.
