CAJ | 학술논문

和肽素(ct-proAVP或copeptin)是一种新型的下丘脑和神经垂体中的神经激素.由于其结构和检测方法的优势逐渐取代抗利尿激素,被视为非特异性应激反应的一个重要标志,近年来ct-proAVP的检测逐渐受到临床的关注,尤其在心血管疾病(心力衰竭和急性冠状动脉综合征等).本文阐述了ct-proAVP的检测优势、方法以及其在各种心血管疾病中的临床价值.
화태소(ct-proAVP혹copeptin)시일충신형적하구뇌화신경수체중적신경격소.유우기결구화검측방법적우세축점취대항이뇨격소,피시위비특이성응격반응적일개중요표지,근년래ct-proAVP적검측축점수도림상적관주,우기재심혈관질병(심력쇠갈화급성관상동맥종합정등).본문천술료ct-proAVP적검측우세、방법이급기재각충심혈관질병중적림상개치.
Copeptin,the C-terminal portion of provasopressin,is a novel neurohormone of the arginine vasopressin (AVP)system,and is known to be co-released with AVP from hypothalamus.As a surrogate marker of the AVP system,copeptin has gradually replaced AVP in several clinical studies largely due to its structural and methodological advantages.Copeptin has been regarded as a marker of non-specific stress response.In recent years,copeptin attracts more and more attention especially in cardiovascular conditions (heart failure and acute coronary syndromes).The present review primarily focuses on copeptin detection,its general advantages,and its potential clinical value in a variety of cardiovascular conditions.