CAJ | 학술논문

液相芯片技术平台为临床诊断中的多重指标分析及批量标本检测提供了自动化的检测手段,可以从少量样本中快速得到大量的辅助诊断信息,正逐步从科学研究实验室进入临床实验室,在多种肿瘤标志物联合检测、自身抗体筛查、人类白细胞抗原(HLA)分型及感染性病原体基因检测等方面具有重要的临床应用价值.但目前仍存在较多制约该技术广泛应用于临床诊断的因素,应进一步做好组合项目的开发及检测的规范化工作,充分利用这一高通量、高灵敏度和高重复性的检测平台,为临床疾病的诊断、治疗及预防提供科学、准确的实验室依据.
액상심편기술평태위림상진단중적다중지표분석급비량표본검측제공료자동화적검측수단,가이종소량양본중쾌속득도대량적보조진단신식,정축보종과학연구실험실진입림상실험실,재다충종류표지물연합검측、자신항체사사、인류백세포항원(HLA)분형급감염성병원체기인검측등방면구유중요적림상응용개치.단목전잉존재교다제약해기술엄범응용우림상진단적인소,응진일보주호조합항목적개발급검측적규범화공작,충분이용저일고통량、고령민도화고중복성적검측평태,위림상질병적진단、치료급예방제공과학、준학적실험실의거.
Suspension array technology,a bead-based multiplex assay,allows a fast and automatic detection of multi-analytes and batch samples in limited sample volume,and it is great potential clinical application in the determination of autoimmune antibodies,muhitumor markers,the phenotype of Human Leukocyte Antigen and the genes of infectious pathogens.However,currently,there are various limitations which hinder the clinical application of this technology broadly.The globally accepted panel of multi analytes,performance criteria,and quality control programs should be established before we get benefit from this high throughput,sensitivity and repeatability platform,which will help to provide scientific and accurate laboratory data for the clinical diagnosis,treatment and prevention.