CAJ | 학술논문

目的探讨手术去核处理联合定期注射复方倍他米松(得宝松)治疗耳廓瘢痕疙瘩的临床效果.方法 2008年1月至2012年1月,治疗186例耳廓瘢痕疙瘩患者,前期根据瘢痕疙瘩大小及患者意愿进行单纯手术(22例)或者单纯注射得宝松(34例)治疗,后期开始进行手术去核处理后定期注射得宝松治疗(130例),所有疗程结束后回访1年,观察并评价3种治疗方法的疗效,将各组数据使用SPSS 16.0软件作统计学处理和分析,并使用GraphPad检验方法进行检验.结果单纯手术治疗患者术后有效率仅为54.55％ (12/22);单纯得宝松注射组患者瘢痕疙瘩在治疗范围期间皆有所减小,各项临床症状都有所减轻,但停药后,逆转现象明显,有效率为55.88％ (19/34);手术去核处理后定期注射得宝松组患者治愈率高,复发病例仅为4例,有效率可高达96.92％(126/130),效果明显优于单纯手术或单纯得宝松注射(P＜0.01).结论手术去核处理联合得宝松注射可以较好地治疗耳廓瘢痕疙瘩.
목적 탐토수술거핵처리연합정기주사복방배타미송(득보송)치료이곽반흔흘탑적림상효과.방법 2008년1월지2012년1월,치료186례이곽반흔흘탑환자,전기근거반흔흘탑대소급환자의원진행단순수술(22례)혹자단순주사득보송(34례)치료,후기개시진행수술거핵처리후정기주사득보송치료(130례),소유료정결속후회방1년,관찰병평개3충치료방법적료효,장각조수거사용SPSS 16.0연건작통계학처리화분석,병사용GraphPad검험방법진행검험.결과 단순수술치료환자술후유효솔부위54.55％ (12/22);단순득보송주사조환자반흔흘탑재치료범위기간개유소감소,각항림상증상도유소감경,단정약후,역전현상명현,유효솔위55.88％ (19/34);수술거핵처리후정기주사득보송조환자치유솔고,복발병례부위4례,유효솔가고체96.92％(126/130),효과명현우우단순수술혹단순득보송주사(P＜0.01).결론 수술거핵처리연합득보송주사가이교호지치료이곽반흔흘탑.
Objective To investigate the treatment of auricular keloid with denuclear surgery and intralesional injection of compound Betamethasone.Methods From Jan.2008 to Jan.2012,a total of 186 cases of ear keloid were treated by surgery only (22 cases),or intralesional injection of compound Betamethasone(34 cases),or combined denuclear surgry with compound Betamethasone(130 cases).All the patients were followed up for one year.SPSS 16.0 software was used for statistical processing and analysis,and GraphPad inspection method for inspection.Results The effective rate was 54.55％ (12/ 22)in surgery group and 55.88％ (19/34)in injection group.The recurrence was obvious in injection group during the follow-up period.The effective rate was as high as 96.92％ (126/130) in combined group with recurrence in 4 cases,which was significantly higher than that in other 2 groups (P ＜ 0.01).Conclusion Combined denuclear surgery and compound Betamethasone injection has a good therapeutic effect on auricular keloids.