CAJ | 학술논문

近年来,JAK-STAT信号转导途径日渐成为研究的热点.JAK和STAT是细胞内和受体相结合的蛋门质,完成从胞质到核内的信号转导.由于该途径直接参与卵巢癌的发生及进展,采取适当方法f预甚至阻断该途径能不同程度抑制肿瘤增殖并促进其凋亡.
근년래,JAK-STAT신호전도도경일점성위연구적열점.JAK화STAT시세포내화수체상결합적단문질,완성종포질도핵내적신호전도.유우해도경직접삼여란소암적발생급진전,채취괄당방법f예심지조단해도경능불동정도억제종류증식병촉진기조망.
Recently,JAK-STAT signal transduction pathway has become a hot spot in research.JAK and STAT are a kind of protein of combination of intracellular and receptor.They can transduct the signal from the cytoplasm to the nucleus.This signal transduction pathway can directly involve in the occurrence and progress of ovarian carcinoma,so taking appropriate methods can intervene or even block the pathway to inhibit tumor proliferation in different degrees and promote their apoptosis.