CAJ | 학술논문

目的对欧洲癌症研究组织(EORTC)头颈癌生存质量问卷(QLQ-H&N35)进行计量心理学考核,以考评量表是否适合于鼻咽癌患者生存质量的测评.方法收集中山大学肿瘤防治中心的391例鼻咽癌患者的QLQ-H&N35和人口学资料,考核量表的信度、效度、区分度,条目进行项目反应理论(IRT)分析,考察个体分离指数(PSI)、条目阈值参数的排序,进行项目功能差异(DIF)分析.结果除感觉问题外,各个领域的内部一致性信度和分半系数均大于0.7,所有领域的重测系数都大于0.7,因子分析的结果显示实际的数据跟理论模型一致.不同放疗阶段的患者在大部分领域得分的差异具有统计学意义.整个模型的PSI为0.90,大部分条目的阈值顺序均正常,所有条目在性别、年龄分组上没有一致性DIF和非一致性DIF.结论 QLQ-H&N35是一个具有良好的信度、效度、区分度和计量心理学特征的癌症量表,可操作性强,可用于鼻咽癌患者的生存质量评价.
목적 대구주암증연구조직(EORTC)두경암생존질량문권(QLQ-H&N35)진행계량심이학고핵,이고평량표시부괄합우비인암환자생존질량적측평.방법 수집중산대학종류방치중심적391례비인암환자적QLQ-H&N35화인구학자료,고핵량표적신도、효도、구분도,조목진행항목반응이론(IRT)분석,고찰개체분리지수(PSI)、조목역치삼수적배서,진행항목공능차이(DIF)분석.결과 제감각문제외,각개영역적내부일치성신도화분반계수균대우0.7,소유영역적중측계수도대우0.7,인자분석적결과현시실제적수거근이론모형일치.불동방료계단적환자재대부분영역득분적차이구유통계학의의.정개모형적PSI위0.90,대부분조목적역치순서균정상,소유조목재성별、년령분조상몰유일치성DIF화비일치성DIF.결론 QLQ-H&N35시일개구유량호적신도、효도、구분도화계량심이학특정적암증량표,가조작성강,가용우비인암환자적생존질량평개.
Objective To assess the psychological characteristics of EORTC QLQ-H&N35 scale,and to explore whether QLQ-H&N35 scale is suitable to measure the qulity of life (QOL) in nasopharyngeal carcinoma (NPC) patients.Methods The data of 391 NPC patients from Cancer Hospital of Sun Yat-Sen University was collected.Split-half reliability,Cronbach's α coefficient,content validity,construct validity,discriminant validity,and feasibility of QLQ-H&N35 were performed.Person separation index (PSI),the order of item threshold,and differential item functioning were analyzed.Results Cronbach'sα coefficient and split-half reliability of QLQ-H&N35 were higher than 0.7,except for sense parameter.All Test-retest coefficients of QLQ-H&N35 were higher than 0.7.The result of factor analysis showed that the data was consistent with the theoretical model.Most of the domain scores and dimension scores of patients with different radiotherapy stages were significantly different (P ＜ 0.05).PSI of the model was 0.90.Most of the order of item threshold were normal.All the items had no uniform or non-uniform DIF among different genders and age groups.Conclusion QLQ-H&N35 scale is a reliable,operable,and valid disease-specific scale for the evaluation QOL in NPC patients.