肿瘤研究与临床
腫瘤研究與臨床
종류연구여림상
CANCER RESEARCH AND CLINIC
2013年
3期
145-147
,共3页
张宏艳%梁峰%刘畅%贾志凌
張宏豔%樑峰%劉暢%賈誌凌
장굉염%량봉%류창%가지릉
肺肿瘤%角蛋白19%CYFRA21-1
肺腫瘤%角蛋白19%CYFRA21-1
폐종류%각단백19%CYFRA21-1
Lung neoplasms%Karatin-19%CYFRA21-1
目的 探讨新型肿瘤标志物细胞角蛋白19片段2G2(CK19-2G2)血清水平对肺癌的诊断价值.方法 采用化学发光法检测并比较了150例肺癌、50例肺炎和150名健康体检者空腹血清中CK19-2G2水平,对比血清CK19-2G2与CYFRA21-1水平对肺癌的诊断效能.结果 CK19-2G2诊断肺癌的敏感度和准确度分别为55.3％(83/150)、80.3％(281/350),而CYFRA21-1诊断肺癌的敏感度和准确度分别为28.0％(42/150)、67.4％(236/350).CK19-2G2敏感度和准确度高于CYFRA21-1(P＜ 0.001).结论 新型肿瘤标志物CK19-2G2血清水平能够起到肺癌临床辅助诊断的作用.
目的 探討新型腫瘤標誌物細胞角蛋白19片段2G2(CK19-2G2)血清水平對肺癌的診斷價值.方法 採用化學髮光法檢測併比較瞭150例肺癌、50例肺炎和150名健康體檢者空腹血清中CK19-2G2水平,對比血清CK19-2G2與CYFRA21-1水平對肺癌的診斷效能.結果 CK19-2G2診斷肺癌的敏感度和準確度分彆為55.3％(83/150)、80.3％(281/350),而CYFRA21-1診斷肺癌的敏感度和準確度分彆為28.0％(42/150)、67.4％(236/350).CK19-2G2敏感度和準確度高于CYFRA21-1(P＜ 0.001).結論 新型腫瘤標誌物CK19-2G2血清水平能夠起到肺癌臨床輔助診斷的作用.
목적 탐토신형종류표지물세포각단백19편단2G2(CK19-2G2)혈청수평대폐암적진단개치.방법 채용화학발광법검측병비교료150례폐암、50례폐염화150명건강체검자공복혈청중CK19-2G2수평,대비혈청CK19-2G2여CYFRA21-1수평대폐암적진단효능.결과 CK19-2G2진단폐암적민감도화준학도분별위55.3％(83/150)、80.3％(281/350),이CYFRA21-1진단폐암적민감도화준학도분별위28.0％(42/150)、67.4％(236/350).CK19-2G2민감도화준학도고우CYFRA21-1(P＜ 0.001).결론 신형종류표지물CK19-2G2혈청수평능구기도폐암림상보조진단적작용.
Objective To investigate the diagnostic value of a new tumor marker CK19-2G2 for lung cancer.Methods The serum levels of CK19-2G2 in 150 lung cancer patients,50 pulmonitis patients and 50 healthy controls were detected with chemoluminescence.The diagnostic efficacy between the serum levels of CK19-2G2 and CYFRA21-1 were compared.Results The sensitivity and accuracy of CK19-2G2 were 55.3 ％ (83/150) and 80.3 ％ (281/350),respectively,while the sensitivity and accuracy of CYFRA21-1 were 28.0 ％ (42/150) and 67.4 ％ (236/350),respectively.The differences were significant (P ＜ 0.001).Conclusion The detection of CK19-2G2 may be a new diagnostic tumor marker for lung cancer.
