CAJ | 학술논문

目的探讨乳腺癌患者自身免疫与非自身免疫甲状腺疾病的发病情况.方法选择100例乳腺癌手术患者,以同期相对应年龄无乳腺疾病及甲状腺疾病病史女性100名为对照组,通过临床检查、B型超声、甲状腺素及抗体水平检查、细针穿刺活组织检查等对比甲状腺疾病的发病情况.结果乳腺癌患者抗甲状腺过氧化物酶抗体明显高于对照组[(104.56±21.54)U/ml比(22.16±4.65)U/m],P=0.030].乳腺癌组自身免疫与非自身免疫甲状腺疾病的发病率高于对照组[38 ％(38/100)比17％(17/100),P=0.0009;26％(26/100)与9％(9/100),P=0.0016].结论乳腺癌患者的自身免疫与非自身免疫甲状腺疾病的发病率高于非乳腺癌者.
목적 탐토유선암환자자신면역여비자신면역갑상선질병적발병정황.방법 선택100례유선암수술환자,이동기상대응년령무유선질병급갑상선질병병사녀성100명위대조조,통과림상검사、B형초성、갑상선소급항체수평검사、세침천자활조직검사등대비갑상선질병적발병정황.결과 유선암환자항갑상선과양화물매항체명현고우대조조[(104.56±21.54)U/ml비(22.16±4.65)U/m],P=0.030].유선암조자신면역여비자신면역갑상선질병적발병솔고우대조조[38 ％(38/100)비17％(17/100),P=0.0009;26％(26/100)여9％(9/100),P=0.0016].결론 유선암환자적자신면역여비자신면역갑상선질병적발병솔고우비유선암자.
Objective To investigate the incidence of autoimmune and nonautoimmune thyroid diseases in patients with breast cancer.Methods Clinical and ultrasound evaluation of thyroid gland,detection of serum thyroid hormone and related antibodies,and fine-needle aspiration of thyroid gland were performed in 100 breast cancer patients and 100 control individuals during the period from 2004 to 2008.Results The mean values of anti-thyroid peroxidase antibodies were significantly higher in breast cancer patients than that in control individuals [(104.56±21.54) U/ml vs (22.16±4.65) U/ml,(P=0.030)].The incidence rates of autoimmune and nonautoimmune thyroid diseases were higher in breast cancer patients than that in control individuals[38 ％ (38/100) vs 17 ％ (17/100),P=0.0009,26 ％ (26/100) vs 9 ％ (9/100),P =0.0016,respectively].Conclusion The results indicate an increased incidence of autoimmune and nonautoimmune thyroid diseases in breast cancer patients.