肿瘤研究与临床
腫瘤研究與臨床
종류연구여림상
CANCER RESEARCH AND CLINIC
2013年
7期
460-462
,共3页
张静芳%郭梅%杨海军%原玉芬
張靜芳%郭梅%楊海軍%原玉芬
장정방%곽매%양해군%원옥분
乳腺肿瘤%青年女性%病理学,临床
乳腺腫瘤%青年女性%病理學,臨床
유선종류%청년녀성%병이학,림상
Breast neoplasms%Young women%Pathology,clinical
目的 探讨青年女性乳腺癌的临床病理特点.方法 回顾性分析201例35岁以下青年女性乳腺癌(青年组)的临床及病理资料,并与随机数字表法分段抽取同期收治的60岁以上老年女性乳腺癌251例(老年组)进行比较,所有病例均经手术治疗及病理证实.结果 青年组乳腺癌病程≤6个月者所占比例高于老年组[82.09%(165/201)、72.11%(181/251)],差异有统计学意义(x2=6.19,P<0.05);青年组原发肿瘤直径≤2 cm的患者比例低于老年组[19.90%(40/201)、30.28 %(76/251)](x2=6.302,P<0.05),淋巴结转移率高于老年组[63.68%(128/201)、54.19%(136/251)](x2 =4.145,P< 0.05);青年组0~Ⅰ期患者比例低于老年组[11.94 %(24/201)、17.53 %(44/251)](x2=2.729,P> 0.05).结论 青年乳腺癌患者就诊时肿瘤直径大,pTNM分期晚,淋巴结转移率高,病情进展较快,危险性较高,但患者警惕性较低.应大力提倡自我体检、定期体检,力争早期发现、早期诊断、早期治疗.
目的 探討青年女性乳腺癌的臨床病理特點.方法 迴顧性分析201例35歲以下青年女性乳腺癌(青年組)的臨床及病理資料,併與隨機數字錶法分段抽取同期收治的60歲以上老年女性乳腺癌251例(老年組)進行比較,所有病例均經手術治療及病理證實.結果 青年組乳腺癌病程≤6箇月者所佔比例高于老年組[82.09%(165/201)、72.11%(181/251)],差異有統計學意義(x2=6.19,P<0.05);青年組原髮腫瘤直徑≤2 cm的患者比例低于老年組[19.90%(40/201)、30.28 %(76/251)](x2=6.302,P<0.05),淋巴結轉移率高于老年組[63.68%(128/201)、54.19%(136/251)](x2 =4.145,P< 0.05);青年組0~Ⅰ期患者比例低于老年組[11.94 %(24/201)、17.53 %(44/251)](x2=2.729,P> 0.05).結論 青年乳腺癌患者就診時腫瘤直徑大,pTNM分期晚,淋巴結轉移率高,病情進展較快,危險性較高,但患者警惕性較低.應大力提倡自我體檢、定期體檢,力爭早期髮現、早期診斷、早期治療.
목적 탐토청년녀성유선암적림상병리특점.방법 회고성분석201례35세이하청년녀성유선암(청년조)적림상급병리자료,병여수궤수자표법분단추취동기수치적60세이상노년녀성유선암251례(노년조)진행비교,소유병례균경수술치료급병리증실.결과 청년조유선암병정≤6개월자소점비례고우노년조[82.09%(165/201)、72.11%(181/251)],차이유통계학의의(x2=6.19,P<0.05);청년조원발종류직경≤2 cm적환자비례저우노년조[19.90%(40/201)、30.28 %(76/251)](x2=6.302,P<0.05),림파결전이솔고우노년조[63.68%(128/201)、54.19%(136/251)](x2 =4.145,P< 0.05);청년조0~Ⅰ기환자비례저우노년조[11.94 %(24/201)、17.53 %(44/251)](x2=2.729,P> 0.05).결론 청년유선암환자취진시종류직경대,pTNM분기만,림파결전이솔고,병정진전교쾌,위험성교고,단환자경척성교저.응대력제창자아체검、정기체검,력쟁조기발현、조기진단、조기치료.
Objective To explore the clinicopathological characteristics in young women with breast cancer.Methods The clinicopathological data of 201 cases of breast cancer with age below 35 years from Apr.1997 to Apr.2010 in Anyang Tumor Hospital were retrospectively analyzed and compared with those of 251 cases of breast cancer patients selected randomly with age more than 60 years during the same period.All these cases had undergone surgical treatment and been confirmed by pathologist.Results In the young group,the percentage of patients with the course of disease less than six months was higher than that of the old-aged group [82.09 % (165/201),72.11% (181/251)] (x2 =6.19,P < 0.05).The incidence of the tumor size ≤ 2 cm in the young group was less than that of the old-aged group [19.90 % (40/201),30.28 % (76/ 251)] (x2 =6.302,P < 0.05).The incidence rate of metastasis of lymph nodes in the young group was less than that of the old-aged group [63.68 % (128/201),54.19 % (136/251)] (x2 =4.145,P < 0.05).The incidence rate of stage 0~ Ⅰ in the young group was more than that of the old-aged group [11.94 % (24/201),17.53 % (44/251)] (x2 =2.729,P > 0.05).Conclusion The tumor size in the young group is larger than that in the old-aged group,pTNM classification in the young group is later than that in the latter group and the incidence rate of metastasis of lymph nodes in the young group is higher than that in the latter group.In young patients with breast cancer the percentage of tumors with advanced tumor stage and poor prognosis are more than that in elder breast cancer patients.In addition,these young patients have lower awareness to mammary adenocarcinoma.Young ladies should examine breast cancer by themselves and go to hospital for regular inspections in order to discovere,diagnose and treat cancer earlier.