肿瘤研究与临床
腫瘤研究與臨床
종류연구여림상
CANCER RESEARCH AND CLINIC
2013年
10期
659-662
,共4页
袁运水%刘龙阳%易娟娟%聂道梅%陈惠祯
袁運水%劉龍暘%易娟娟%聶道梅%陳惠禎
원운수%류룡양%역연연%섭도매%진혜정
子宫颈肿瘤%肿瘤浸润%Ⅰ型子宫切除术%可行性研究
子宮頸腫瘤%腫瘤浸潤%Ⅰ型子宮切除術%可行性研究
자궁경종류%종류침윤%Ⅰ형자궁절제술%가행성연구
Uterine cervical neoplasms%Neoplasm invasiveness%Type Ⅰ hysterectomy%Feasibility study
目的 比较子宫颈癌ⅠA期采用Ⅰ型和Ⅱ型子宫切除术的疗效及并发症,探索Ⅰ型子宫切除术用于ⅠA期子宫颈癌的可行性.方法 对92例子宫颈癌患者(48例ⅠA1期,44例ⅠA2期)行Ⅰ型子宫切除术加选择性盆腔淋巴结切除(研究组),对93例子宫颈癌患者(49例ⅠA1期,44例ⅠA2期)行Ⅱ型子宫切除术加选择性盆腔淋巴结切除(对照组).结果 研究组5年和10年生存率分别为100 ％(92/92)、100％(74/74),对照组分别为100 ％(93/93)、100％(66/66).研究组泌尿道感染率为0(0/92),低于对照组的13.99％(13/93)(P＜0.05).研究组的手术时间、出血量和人均输血量分别为(96.14±17.20)min、(117.35±39.61)ml和0 ml,均较对照组[(116.82±16.30)min、(201.74±46.25) ml、(82.07±16.32) ml]减少,差异均有统计学意义(P＜0.01).结论 子宫颈癌ⅠA期患者采用Ⅰ型和Ⅱ型子宫切除术的5年和10年生存率相当,但前者术后泌尿道感染率低于后者,且手术时间缩短,出血量和输血量均减少,其用于ⅠA期子宫颈癌是有效的、可行的.
目的 比較子宮頸癌ⅠA期採用Ⅰ型和Ⅱ型子宮切除術的療效及併髮癥,探索Ⅰ型子宮切除術用于ⅠA期子宮頸癌的可行性.方法 對92例子宮頸癌患者(48例ⅠA1期,44例ⅠA2期)行Ⅰ型子宮切除術加選擇性盆腔淋巴結切除(研究組),對93例子宮頸癌患者(49例ⅠA1期,44例ⅠA2期)行Ⅱ型子宮切除術加選擇性盆腔淋巴結切除(對照組).結果 研究組5年和10年生存率分彆為100 ％(92/92)、100％(74/74),對照組分彆為100 ％(93/93)、100％(66/66).研究組泌尿道感染率為0(0/92),低于對照組的13.99％(13/93)(P＜0.05).研究組的手術時間、齣血量和人均輸血量分彆為(96.14±17.20)min、(117.35±39.61)ml和0 ml,均較對照組[(116.82±16.30)min、(201.74±46.25) ml、(82.07±16.32) ml]減少,差異均有統計學意義(P＜0.01).結論 子宮頸癌ⅠA期患者採用Ⅰ型和Ⅱ型子宮切除術的5年和10年生存率相噹,但前者術後泌尿道感染率低于後者,且手術時間縮短,齣血量和輸血量均減少,其用于ⅠA期子宮頸癌是有效的、可行的.
목적 비교자궁경암ⅠA기채용Ⅰ형화Ⅱ형자궁절제술적료효급병발증,탐색Ⅰ형자궁절제술용우ⅠA기자궁경암적가행성.방법 대92례자궁경암환자(48례ⅠA1기,44례ⅠA2기)행Ⅰ형자궁절제술가선택성분강림파결절제(연구조),대93례자궁경암환자(49례ⅠA1기,44례ⅠA2기)행Ⅱ형자궁절제술가선택성분강림파결절제(대조조).결과 연구조5년화10년생존솔분별위100 ％(92/92)、100％(74/74),대조조분별위100 ％(93/93)、100％(66/66).연구조비뇨도감염솔위0(0/92),저우대조조적13.99％(13/93)(P＜0.05).연구조적수술시간、출혈량화인균수혈량분별위(96.14±17.20)min、(117.35±39.61)ml화0 ml,균교대조조[(116.82±16.30)min、(201.74±46.25) ml、(82.07±16.32) ml]감소,차이균유통계학의의(P＜0.01).결론 자궁경암ⅠA기환자채용Ⅰ형화Ⅱ형자궁절제술적5년화10년생존솔상당,단전자술후비뇨도감염솔저우후자,차수술시간축단,출혈량화수혈량균감소,기용우ⅠA기자궁경암시유효적、가행적.
Objective To compare the efficacy and complications of the two surgical methods (between type Ⅰ hysterectomy and type Ⅱ hysterectomy),and to explore the feasibility of type Ⅰ hysterectomy in stage ⅠA cervical cancer.Methods The study group,92 cases(48 cases of stage ⅠA1,44 cases of stage ⅠA2) were performed with type Ⅰ hysterectomy plus selective pelvic lymph node dissection;the control group,93 cases (49 cases of stage ⅠA1,44 cases of ⅠA2) were performed with type Ⅱ hysterectomy plus selective pelvic lymph node dissection.Results The survival rate of 5 years and 10 years in study group were 100 ％ (92/92),100 ％ (74/74) and that in control group were 100 ％ (93/93),100 ％(66/66),respectively.There were no signicant difference between the two group (both P ＞ 0.05).When compared with the control group,the urinary tract infection of the study group was significantly reduced (0 versus 13.99 ％,P ＜ 0.05).Moreover,there were a shorter surgical duration [(96.14±17.20) min vs (116.82±16.30) min].The hemorrhage [(117.35±39.61) ml] and blood transfusion (0 ml) in study group was less common than those in control group [(201.74±46.25) ml,(82.07±16.32) ml] (all P ＜ 0.01).Conclusion There are no difference of 5-year and l0-year survival rate in stage ⅠA patients with type Ⅰ or type Ⅱ hysterectomy,however,the rate of the postoperative urinary tract infection in the former is lower than that in the latter,and also there are a shorter surgical duration,less hemorrhage and reduced blood transfusion requirements in study group.Therefore,type Ⅰ hysterectomy can be effective and applicable for the patients of stage ⅠA cervical cancer.
