肿瘤研究与临床
腫瘤研究與臨床
종류연구여림상
CANCER RESEARCH AND CLINIC
2014年
5期
294-297
,共4页
刘琪%张旭婷%靳宏星%任基伟
劉琪%張旭婷%靳宏星%任基偉
류기%장욱정%근굉성%임기위
孤立性肺结节%CT能谱成像%诊断,鉴别
孤立性肺結節%CT能譜成像%診斷,鑒彆
고립성폐결절%CT능보성상%진단,감별
Solitary pulmonary nodules%CT spectral imaging%Diagnosis,differential
目的 探讨宝石能谱CT在孤立性肺结节(SPN)诊断及鉴别诊断中的应用价值.方法 回顾性分析接受胸部CT高压三期检查的32例SPN病例资料.所有病例经手术、穿刺活组织检查后病理证实.所有检查均在宝石能谱CT上进行,扫描完成后将单能量图像载入宝石能谱成像浏览器(GSI viewer)软件上,对SPN的能谱曲线图及碘基图像碘含量和水基图像水含量进行分析.结果 肺鳞状细胞癌、肺腺癌、错构瘤、硬化性血管瘤、炎性假瘤碘含量分别为(11.66±2.72) μg/ml、(12.36±2.97) μg/ml、(10.20±3.11) μg/ml、(16.58±3.58) μg/ml、(21.67±3.76) μg/ml,肺腺癌及肺鳞状细胞癌的碘含量之间差异无统计学意义(P＞0.05),其他不同结节的碘含量之间差异均有统计学意义(均P＜ 0.05).肺鳞状细胞癌、肺腺癌、错构瘤、硬化性血管瘤、炎性假瘤的水含量分别为(1 021.31±13.83) μg/ml、(1 027.98±12.53)μg/ml、(1 003.42±13.67) μg/ml、(1 029.61±12.06)μg/ml、(1 051.61±13.81)μg/ml,各类不同结节的水含量之间差异无统计学意义(均P＞0.05).结论 宝石能谱CT成像通过应用碘含量测定,对鉴别不同来源的SPN有较大意义,可以提高SPN良恶性鉴别诊断的敏感性及特异性.
目的 探討寶石能譜CT在孤立性肺結節(SPN)診斷及鑒彆診斷中的應用價值.方法 迴顧性分析接受胸部CT高壓三期檢查的32例SPN病例資料.所有病例經手術、穿刺活組織檢查後病理證實.所有檢查均在寶石能譜CT上進行,掃描完成後將單能量圖像載入寶石能譜成像瀏覽器(GSI viewer)軟件上,對SPN的能譜麯線圖及碘基圖像碘含量和水基圖像水含量進行分析.結果 肺鱗狀細胞癌、肺腺癌、錯構瘤、硬化性血管瘤、炎性假瘤碘含量分彆為(11.66±2.72) μg/ml、(12.36±2.97) μg/ml、(10.20±3.11) μg/ml、(16.58±3.58) μg/ml、(21.67±3.76) μg/ml,肺腺癌及肺鱗狀細胞癌的碘含量之間差異無統計學意義(P＞0.05),其他不同結節的碘含量之間差異均有統計學意義(均P＜ 0.05).肺鱗狀細胞癌、肺腺癌、錯構瘤、硬化性血管瘤、炎性假瘤的水含量分彆為(1 021.31±13.83) μg/ml、(1 027.98±12.53)μg/ml、(1 003.42±13.67) μg/ml、(1 029.61±12.06)μg/ml、(1 051.61±13.81)μg/ml,各類不同結節的水含量之間差異無統計學意義(均P＞0.05).結論 寶石能譜CT成像通過應用碘含量測定,對鑒彆不同來源的SPN有較大意義,可以提高SPN良噁性鑒彆診斷的敏感性及特異性.
목적 탐토보석능보CT재고립성폐결절(SPN)진단급감별진단중적응용개치.방법 회고성분석접수흉부CT고압삼기검사적32례SPN병례자료.소유병례경수술、천자활조직검사후병리증실.소유검사균재보석능보CT상진행,소묘완성후장단능량도상재입보석능보성상류람기(GSI viewer)연건상,대SPN적능보곡선도급전기도상전함량화수기도상수함량진행분석.결과 폐린상세포암、폐선암、착구류、경화성혈관류、염성가류전함량분별위(11.66±2.72) μg/ml、(12.36±2.97) μg/ml、(10.20±3.11) μg/ml、(16.58±3.58) μg/ml、(21.67±3.76) μg/ml,폐선암급폐린상세포암적전함량지간차이무통계학의의(P＞0.05),기타불동결절적전함량지간차이균유통계학의의(균P＜ 0.05).폐린상세포암、폐선암、착구류、경화성혈관류、염성가류적수함량분별위(1 021.31±13.83) μg/ml、(1 027.98±12.53)μg/ml、(1 003.42±13.67) μg/ml、(1 029.61±12.06)μg/ml、(1 051.61±13.81)μg/ml,각류불동결절적수함량지간차이무통계학의의(균P＞0.05).결론 보석능보CT성상통과응용전함량측정,대감별불동래원적SPN유교대의의,가이제고SPN량악성감별진단적민감성급특이성.
Objective To explore the value of gemstone spectral imaging (GSI) with single source dual-energy CT in characterizing the benign and malignant solitary pulmonary nodules (SPN).Methods Totally 32 patients with SPN underwent phaseⅢ enhanced CT scan using single source dual-energy CT by GSI mode.Three types of images were reconstructed for analysis:the water concentration (WC),iodine concentration (IC) and normalized iodine concentration (NIC).Results The IC of lung squamous cell carcinoma lung adenocarcinoma,hamartoma,sclerosing hemangioma,inflammatory pseudotumor were (11.66± 2.72) μg/ml,(12.36±2.97) μg/ml,(10.20±3.11) μg/ml,(16.58±3.58) μg/ml,(21.67±3.76) μg/ml,the IC of lung adenocarcinoma and lung squamous cell carcinoma had no difference (P ＞ 0.05),there were significant differences in the value of iodine material between other nodules (all P ＜ 0.05).The WC of lung adenocarcinoma,lung squamous cell carcinoma,hamartoma,sclerosing hemangioma,inflammatory pseudotumor were (1 021.31±13.83) μg/ml,(1 027.98±12.53) μg/ml,(1 003.42±13.67) μg/ml,(1 029.61±12.06) μg/ml,(1 051.61±13.81) μg/ml,there was no significant difference in the value of water material between nodules (all P ＞ 0.05).Conclusion The spectral CT imaging may be helpful for characterizing the pathological type of SPN.
