CAJ | 학술논문

目的探讨磁共振成像(MRI)结合血清CA125水平检测在卵巢肿瘤诊断中的价值.方法对健康人40名、卵巢良性病变患者52例及卵巢恶性肿瘤患者43例进行MRI及血清CA125水平检测,判定联合检查及单一检查对卵巢肿瘤诊断的准确性.结果 CA125对卵巢肿块的诊断敏感度为79.3％,特异度为72.6％、准确率为75.1％;MRI的敏感度为73.8％、特异度为81.2％、准确率为82.6％;二者联合检查的敏感度为69.4％、特异度为97.3％、准确率为88.6％,联合检查与单一检查的尤登指数差异有统计学意义(MRI联合血清CA125检查卵巢肿块与单独使用MRI检查比较,u=1.97,P=0.012 5;联合检查较单一使用血清CA125检查比较,u=1.96,P=0.0120).结论 MRI与血清CA125联合检查能提高卵巢肿瘤诊断的准确性,在临床上减少误诊率,是一种值得推广的检查方法.
목적 탐토자공진성상(MRI)결합혈청CA125수평검측재란소종류진단중적개치.방법 대건강인40명、란소량성병변환자52례급란소악성종류환자43례진행MRI급혈청CA125수평검측,판정연합검사급단일검사대란소종류진단적준학성.결과 CA125대란소종괴적진단민감도위79.3％,특이도위72.6％、준학솔위75.1％;MRI적민감도위73.8％、특이도위81.2％、준학솔위82.6％;이자연합검사적민감도위69.4％、특이도위97.3％、준학솔위88.6％,연합검사여단일검사적우등지수차이유통계학의의(MRI연합혈청CA125검사란소종괴여단독사용MRI검사비교,u=1.97,P=0.012 5;연합검사교단일사용혈청CA125검사비교,u=1.96,P=0.0120).결론 MRI여혈청CA125연합검사능제고란소종류진단적준학성,재림상상감소오진솔,시일충치득추엄적검사방법.
Objective To investigate the value of MRI combined with serum CA125 test in the diagnose of ovarian tumor.Methods To investigate the MRI and serum CA125 level of healthy control group (40 cases),benign tumor group (52 cases),and the malignant tumor group (43 cases).Results Of 95 patients with ovarian masses,CA125 was detected in the malignant patients with the sensitivity of 79.3 ％,specificity of 72.6 ％ and accuracy of 75.1％.MRI was 73.8 ％,81.2 ％,and 82.6 ％ respectively.Combined with CA125 and MRI was 69.4 ％,97.3 ％,and 88.6 ％.Youden' s index of combined detection was significantly higher than single detection (MRI combined with CA125 and single MRI u =1.97,P =0.012 5,and CA125 u =1.96,P =0.012 0).Conclusion MRI combined with CA125 could improve the accuracy of diagnosis ovarian neoplasm in clinic.