肿瘤研究与临床
腫瘤研究與臨床
종류연구여림상
CANCER RESEARCH AND CLINIC
2014年
5期
353-356
,共4页
子宫颈上皮内瘤变%子宫颈肿瘤%人类染色体端粒酶基因%扩增
子宮頸上皮內瘤變%子宮頸腫瘤%人類染色體耑粒酶基因%擴增
자궁경상피내류변%자궁경종류%인류염색체단립매기인%확증
Cervical intraepithelial neoplasias%Cervical neoplasms%Human telomerase RNA gene component%Amplification
在子宫颈上皮内瘤变(CIN)进展为浸润性子宫颈癌的过程中,人类染色体端粒酶(hTERC)基因扩增随子宫颈病变的不同阶段而变化,并且对于子宫颈病变的早期诊断及子宫颈癌发展的监测具有重要的临床价值.hTERC基因有望成为子宫颈高危病变筛查的一种有效的特异标志物.
在子宮頸上皮內瘤變(CIN)進展為浸潤性子宮頸癌的過程中,人類染色體耑粒酶(hTERC)基因擴增隨子宮頸病變的不同階段而變化,併且對于子宮頸病變的早期診斷及子宮頸癌髮展的鑑測具有重要的臨床價值.hTERC基因有望成為子宮頸高危病變篩查的一種有效的特異標誌物.
재자궁경상피내류변(CIN)진전위침윤성자궁경암적과정중,인류염색체단립매(hTERC)기인확증수자궁경병변적불동계단이변화,병차대우자궁경병변적조기진단급자궁경암발전적감측구유중요적림상개치.hTERC기인유망성위자궁경고위병변사사적일충유효적특이표지물.
During the progression of cervical intraepithelial neoplasia (CIN) to invasive cervical cancer,human telomerase RNA gene component (hTERC gene) amplification varies with the different stages of cervical lesions.hTERC gene plays an important role in the early diagnosis of cervical lesions and monitoring the development of cervical cancer.hTERC gene is expected to be an effective specific marker in high-risk lesions of cervical screening.
