肿瘤研究与临床
腫瘤研究與臨床
종류연구여림상
CANCER RESEARCH AND CLINIC
2014年
6期
377-380
,共4页
张建新%陈麦林%杜笑松%侯丽娜%辛磊%杨晓棠%王峻
張建新%陳麥林%杜笑鬆%侯麗娜%辛磊%楊曉棠%王峻
장건신%진맥림%두소송%후려나%신뢰%양효당%왕준
食管肿瘤%体层摄影术,X线计算机%宝石能谱成像
食管腫瘤%體層攝影術,X線計算機%寶石能譜成像
식관종류%체층섭영술,X선계산궤%보석능보성상
Esophageal neoplasms%Tomography,X-ray computed%Gemstone spectral imaging
目的 探讨宝石能谱CT在初步判断食管癌病理特点中的应用.方法 58例经手术病理证实的食管癌患者,采用GE宝石能谱成像(GSI)技术行CT增强扫描.利用GSI分析软件测量主动脉期碘基图上病灶的碘基值(IC).对不同病理分级、不同部位、不同病理形态的IC值进行统计学分析与处理.结果 52例鳞状细胞癌的IC值(14.75±4.24) mg/ml,6例腺癌的IC值(12.86±5.09) mg/ml,二者差异无统计学意义(P=0.35).病理分级:高分化癌19例,中分化癌25例,低分化癌14例,其平均IC值分别为(20.08±4.66) mg/ml、(14.13±3.39)mg/ml、(11.73±3.21)mg/ml,三者间差异具有统计学意义(P=0.00).病理形态:髓质型16例,蕈伞型21例,溃疡型13例,缩窄型8例,其平均IC值分别为(16.34±2.56) mg/ml、(18.70±3.03) mg/ml、(14.31±4.60) mg/ml、(11.18±2.09)mg/ml,蕈伞型与缩窄型的IC值差异有统计学意义(P=0.04),其他类型间差异无统计学意义(P=0.19).结论 GSI技术可以进行基物质成像、单能量成像、物质分离,基物质图像的IC值对食管癌病理特征的判断、对治疗的指导及预后的判断均有一定临床价值.
目的 探討寶石能譜CT在初步判斷食管癌病理特點中的應用.方法 58例經手術病理證實的食管癌患者,採用GE寶石能譜成像(GSI)技術行CT增彊掃描.利用GSI分析軟件測量主動脈期碘基圖上病竈的碘基值(IC).對不同病理分級、不同部位、不同病理形態的IC值進行統計學分析與處理.結果 52例鱗狀細胞癌的IC值(14.75±4.24) mg/ml,6例腺癌的IC值(12.86±5.09) mg/ml,二者差異無統計學意義(P=0.35).病理分級:高分化癌19例,中分化癌25例,低分化癌14例,其平均IC值分彆為(20.08±4.66) mg/ml、(14.13±3.39)mg/ml、(11.73±3.21)mg/ml,三者間差異具有統計學意義(P=0.00).病理形態:髓質型16例,蕈傘型21例,潰瘍型13例,縮窄型8例,其平均IC值分彆為(16.34±2.56) mg/ml、(18.70±3.03) mg/ml、(14.31±4.60) mg/ml、(11.18±2.09)mg/ml,蕈傘型與縮窄型的IC值差異有統計學意義(P=0.04),其他類型間差異無統計學意義(P=0.19).結論 GSI技術可以進行基物質成像、單能量成像、物質分離,基物質圖像的IC值對食管癌病理特徵的判斷、對治療的指導及預後的判斷均有一定臨床價值.
목적 탐토보석능보CT재초보판단식관암병리특점중적응용.방법 58례경수술병리증실적식관암환자,채용GE보석능보성상(GSI)기술행CT증강소묘.이용GSI분석연건측량주동맥기전기도상병조적전기치(IC).대불동병리분급、불동부위、불동병리형태적IC치진행통계학분석여처리.결과 52례린상세포암적IC치(14.75±4.24) mg/ml,6례선암적IC치(12.86±5.09) mg/ml,이자차이무통계학의의(P=0.35).병리분급:고분화암19례,중분화암25례,저분화암14례,기평균IC치분별위(20.08±4.66) mg/ml、(14.13±3.39)mg/ml、(11.73±3.21)mg/ml,삼자간차이구유통계학의의(P=0.00).병리형태:수질형16례,심산형21례,궤양형13례,축착형8례,기평균IC치분별위(16.34±2.56) mg/ml、(18.70±3.03) mg/ml、(14.31±4.60) mg/ml、(11.18±2.09)mg/ml,심산형여축착형적IC치차이유통계학의의(P=0.04),기타류형간차이무통계학의의(P=0.19).결론 GSI기술가이진행기물질성상、단능량성상、물질분리,기물질도상적IC치대식관암병리특정적판단、대치료적지도급예후적판단균유일정림상개치.
Objective To evaluate the clinical value of gemstone spectral imaging (GSI) in preliminary assessment of esophageal carcinoma pathology features.Methods 58 patients were analyzed which were diagnosed with histological pathology as esophageal carcinoma underwent GSI enhanced scans before surgery.The iodine concentrations (IC) in the lesions were measured on the iodine-water based material-decomposition images.The results of IC value were evaluated retrospectively with different pathological grading,locations and pathological morphology according to the final pathologic findings.Results 52 cases patients were squamous cell carcinoma and 6 patients were adenocarcinoma.The IC values were (14.75±4.24) mg/ml and (12.86±5.09) mg/ml.The IC value between the two different pathological types had not statistically difference (P =0.35).The IC of different pathological grading:Well differentiation was (20.08± 4.66)mg/ml,n =19.Medium was (14.13±3.39) mg/ml,n =25.Poor was(11.73±3.21) mg/ml,n =14.The IC values between pathological grading had significant difference(P =0.00).There were four different pathological morphology including m edullar (n =16),m ushroom type (n =21),ulcer (n =13) and narrow type (n =8).Their IC values respectively were (16.34±2.56) mg/ml,(18.70±3.03) mg/ml,(14.31±4.60) mg/ml and (11.18±2.09) mg/ml.The IC value between mushroom and narrow type had statistical difference (P =0.04).The Other types had no statistically difference (P =0.19).Conclusions The results of this study demonstrate that GSI has a certain ability of pathologic stage of esophageal cancer.The GSI has a certain clinical value in guiding treatment and judging prognosis of esophageal carcinoma.
