CAJ | 학술논문

目的探讨超声诊断技术在慢性肾功能衰竭(CRF)与原发高血压病(HTN)患者颈动脉血管壁的弹性及僵硬度中的对比研究.方法使用L3-11高频探头在右侧颈内动脉与颈外动脉分叉下方0.5、1.0、2.0 cm处测量舒张期和收缩期颈总动脉内径(Dd,Ds)及内中膜厚度(IMT),求其平均值,并计算血管壁压力应变弹性系数(Ep)、顺应性(AC)、僵硬度(SI)后,对高血压病患者和对照组行左上肢收缩压(收缩压)和舒张压(舒张压)测量.结果颈总动脉的超声参数结果,与对照组比较,CRF组的IMT、Ds、Dd、EP、AC、SI、收缩压、舒张压测值均增高(P＜0.01);HTN组除Ds较对照组升高差异无统计学意义外,余指标测值均升高且差异有统计学意义(P＜0.01);CRF组与HTN组间比较,Ds、Dd、EP、SI、舒张压差异有统计学意义(P＜0.01).结论超声评价CRF患者颈动脉血管壁性质的变化,对了解血管壁的损害提供了一种新的检测手段,具有重要的临床意义.
목적 탐토초성진단기술재만성신공능쇠갈(CRF)여원발고혈압병(HTN)환자경동맥혈관벽적탄성급강경도중적대비연구.방법 사용L3-11고빈탐두재우측경내동맥여경외동맥분차하방0.5、1.0、2.0 cm처측량서장기화수축기경총동맥내경(Dd,Ds)급내중막후도(IMT),구기평균치,병계산혈관벽압력응변탄성계수(Ep)、순응성(AC)、강경도(SI)후,대고혈압병환자화대조조행좌상지수축압(수축압)화서장압(서장압)측량.결과 경총동맥적초성삼수결과,여대조조비교,CRF조적IMT、Ds、Dd、EP、AC、SI、수축압、서장압측치균증고(P＜0.01);HTN조제Ds교대조조승고차이무통계학의의외,여지표측치균승고차차이유통계학의의(P＜0.01);CRF조여HTN조간비교,Ds、Dd、EP、SI、서장압차이유통계학의의(P＜0.01).결론 초성평개CRF환자경동맥혈관벽성질적변화,대료해혈관벽적손해제공료일충신적검측수단,구유중요적림상의의.
Objective To investigate the difference of function of the carotid artery in patients with chronic renal failure (CRF) and primary hypertension (HTN) by ultrasonography.Methods The objects were in prostration and the right common carotid artery were examined by L3-11 probe.The diastolic diameter(Dd),systolic diameter(Ds),intirna-media thickness(IMT) of the right common carotid artery were obtained,then pressure-strain elastic modulus (EP),artery compliance (AC),artery stiffness (SI) were calculated.Finally,the SBP and the DBP of HTN group and control group were collected in the left upper limb.The SBP and DBP of CRF group were collected before and after dialysis.Results Compared with control group,IMT,Ds,Dd,EP,SI,SBP and DBP in CRF group increased significantly and AC decreased significantly (P ＜ 0.01),while the IMT,Dd,EP and SI in HTN group increased significantly and AC decreased significantly (P ＜ 0.01).Compared with HTN group,the Ds,Dd,EP,SI,DBP in CRF group were higher (P ＜ 0.01).Conclusions Ultrasonography plays an important role in assessing the character of vessel in CRF patients.