中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2012年
21期
39-40
,共2页
S100B蛋白%急性大动脉粥样硬化性脑梗死
S100B蛋白%急性大動脈粥樣硬化性腦梗死
S100B단백%급성대동맥죽양경화성뇌경사
S100B protein%Acut atherosclerotic cerebral infarction
目的 观察急性大动脉粥样硬化性脑梗死(AACI)患者血清S100B蛋白水平的变化.方法 采用酶联免疫双抗体夹心法对95例住院的AACI组患者和正常健康组79例进行血清S100B蛋白水平的检测并进行比较,AAC1组并按神经功能缺损程度评分(NFDS)分为轻型、中型、重型三组.结果 AACI组的血清S100B蛋白水平显著高于正常健康组(P＜0.01)；血清S100B蛋白水平与急性脑梗死患者的神经功能缺损程度相关(P均＜0.05),病情越重S100B蛋白含量越高.结论 S100B蛋白水平与AACI患者的病情严重程度相关,提示S100B蛋白水平持续升高者预后不良.
目的 觀察急性大動脈粥樣硬化性腦梗死(AACI)患者血清S100B蛋白水平的變化.方法 採用酶聯免疫雙抗體夾心法對95例住院的AACI組患者和正常健康組79例進行血清S100B蛋白水平的檢測併進行比較,AAC1組併按神經功能缺損程度評分(NFDS)分為輕型、中型、重型三組.結果 AACI組的血清S100B蛋白水平顯著高于正常健康組(P＜0.01)；血清S100B蛋白水平與急性腦梗死患者的神經功能缺損程度相關(P均＜0.05),病情越重S100B蛋白含量越高.結論 S100B蛋白水平與AACI患者的病情嚴重程度相關,提示S100B蛋白水平持續升高者預後不良.
목적 관찰급성대동맥죽양경화성뇌경사(AACI)환자혈청S100B단백수평적변화.방법 채용매련면역쌍항체협심법대95례주원적AACI조환자화정상건강조79례진행혈청S100B단백수평적검측병진행비교,AAC1조병안신경공능결손정도평분(NFDS)분위경형、중형、중형삼조.결과 AACI조적혈청S100B단백수평현저고우정상건강조(P＜0.01)；혈청S100B단백수평여급성뇌경사환자적신경공능결손정도상관(P균＜0.05),병정월중S100B단백함량월고.결론 S100B단백수평여AACI환자적병정엄중정도상관,제시S100B단백수평지속승고자예후불량.
Objective To observe the changes of serum S100B protein levels in patients with acut atherosclerotic cerebral infarction(AACI).Methods The levels of serum S100B protein in 95 patients with AACI and 79 normal controls were measured by double antibody enzyme-linked immunosorbent assays.Patients in AACI were subdivided into mild group,moderate group and severe group according to NFDS.Results The levels of serum S100B protein in patients with AACI were significantly higher than those in control group(P ＜ 0.05).The levels of serum S100B increased with the score of neurofunction detection increased.Conclusions S100B protein is related with the severity of AACI,and the increasing level of S100B protein indicating the poor prognosis.
