中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2012年
23期
59-61
,共3页
曼月乐%子宫内膜息肉%宫腔镜%复发
曼月樂%子宮內膜息肉%宮腔鏡%複髮
만월악%자궁내막식육%궁강경%복발
Mirena%Endometrial polyps%Hysteroscopy%Recurrence
目的 探讨子宫内膜息肉电切术(TCRP)后应用曼月乐预防息肉复发的效果、依从性及对肝肾功能的影响.方法 选择2006年3月至2009年3月在中山市博爱医院妇科行宫腔镜检查+ TCRP并经病理诊断证实的子宫内膜息肉患者218例,随机分为曼月乐组、口服孕激素组和对照组,随访2年,观察子宫内膜息肉复发情况、肝肾功能及依从性.结果 曼月乐组放置曼月乐2年后复发率为0％,口服孕激素组为1.25％,对照组为8.57％,曼月乐组与口服孕激素组比较差异无统计学意义(P＞0.05),曼月乐组、口服孕激素组分别与对照组比较,差异有统计学意义(P＜0.05)；曼月乐组依从率为98.48％,口服孕激素组为87.5％,两组比较差异有统计学意义(P＜0.05)；曼月乐组患者中未发现肝肾功能异常,口服孕激素组患者中有6例出现转氨酶升高,与对照组及曼月乐组比较,差异有统计学意义(P＜0.05).结论 子宫内膜息肉电切术后应用曼月乐治疗有助于预防子宫内膜息肉的复发,对肝肾功能无影响,不良反应小,依从性高.
目的 探討子宮內膜息肉電切術(TCRP)後應用曼月樂預防息肉複髮的效果、依從性及對肝腎功能的影響.方法 選擇2006年3月至2009年3月在中山市博愛醫院婦科行宮腔鏡檢查+ TCRP併經病理診斷證實的子宮內膜息肉患者218例,隨機分為曼月樂組、口服孕激素組和對照組,隨訪2年,觀察子宮內膜息肉複髮情況、肝腎功能及依從性.結果 曼月樂組放置曼月樂2年後複髮率為0％,口服孕激素組為1.25％,對照組為8.57％,曼月樂組與口服孕激素組比較差異無統計學意義(P＞0.05),曼月樂組、口服孕激素組分彆與對照組比較,差異有統計學意義(P＜0.05)；曼月樂組依從率為98.48％,口服孕激素組為87.5％,兩組比較差異有統計學意義(P＜0.05)；曼月樂組患者中未髮現肝腎功能異常,口服孕激素組患者中有6例齣現轉氨酶升高,與對照組及曼月樂組比較,差異有統計學意義(P＜0.05).結論 子宮內膜息肉電切術後應用曼月樂治療有助于預防子宮內膜息肉的複髮,對肝腎功能無影響,不良反應小,依從性高.
목적 탐토자궁내막식육전절술(TCRP)후응용만월악예방식육복발적효과、의종성급대간신공능적영향.방법 선택2006년3월지2009년3월재중산시박애의원부과행궁강경검사+ TCRP병경병리진단증실적자궁내막식육환자218례,수궤분위만월악조、구복잉격소조화대조조,수방2년,관찰자궁내막식육복발정황、간신공능급의종성.결과 만월악조방치만월악2년후복발솔위0％,구복잉격소조위1.25％,대조조위8.57％,만월악조여구복잉격소조비교차이무통계학의의(P＞0.05),만월악조、구복잉격소조분별여대조조비교,차이유통계학의의(P＜0.05)；만월악조의종솔위98.48％,구복잉격소조위87.5％,량조비교차이유통계학의의(P＜0.05)；만월악조환자중미발현간신공능이상,구복잉격소조환자중유6례출현전안매승고,여대조조급만월악조비교,차이유통계학의의(P＜0.05).결론 자궁내막식육전절술후응용만월악치료유조우예방자궁내막식육적복발,대간신공능무영향,불량반응소,의종성고.
Objective To investigate the effect of mirena on prevention of polyp recurrence of transcervical resection of endometrial polyp(TCRP) and its compliance application and effect on liver and kidney function.Methods Two hundred and eighteen cases of endometrial polyps diagnosed by hysteroscopy combined with TCRP and pathologicall confirmed in boai hospital of zhongshan from March 2006 to March 2009 were randomly divided into three groups,the mirena group,oral progesterone group and control group.The follow-up time was 2 years,and the recurrence of endometrial polyps,liver and kidney function,and compliance were observed.Results The recurrence rate was 0％ in mirena group after the patients were placed with mirena for two years,1.25％ in the oral progesterone group 2 years after operation and 8.57％ in the control group,there was no significant difference between mirena group and oral progesterone group (P ＞ 0.05).The mirena group and the oral progesterone group respectively compared with the control group,the differences were significant (P ＜ 0.05).The compliance rate of mirena group (98.48 ％)was obviously higher than that of the oral progesterone group (87.5％),the differences were significants (P ＜ 0.05).There was no abnormal liver and kidney function in mirena group,six cases of elevated transaminase were found in oral progesterone group,there were significant differences by respectively compared with the control group and the Mirena group (P ＜ 0.05).Conclusions Mirena has no influence on the liver and kidney function,little side effect and high compliance for prevention of polyp recurrence of transcervical resection of endometrial polyp.
