中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
1期
4-6
,共3页
急性冠状动脉综合征%超敏C-反应蛋白%溶血磷脂酸%冠状动脉狭窄
急性冠狀動脈綜閤徵%超敏C-反應蛋白%溶血燐脂痠%冠狀動脈狹窄
급성관상동맥종합정%초민C-반응단백%용혈린지산%관상동맥협착
Acute coronary syndrome%High sensitivity C-reactive protein%Lysophosphatidic acid%Coronary artery stenosis
目的 探讨急性冠状动脉综合征患者血浆超敏C-反应蛋白(hs-CRP)、溶血磷脂酸(LPA)与冠状动脉狭窄程度的相关性.方法 131例急性冠状动脉综合征患者分为ST段抬高型心肌梗死(STEMI)组41例、非ST段抬高型心肌梗死(NSTEMI)组42例、不稳型心绞痛(UAP)组48例,再选取30例健康人为对照组.所有入选者测定hs-CRP和LPA,急性冠状动脉的患者行冠状动脉造影判断狭窄的程度.结果 四组间hs-CRP、LPA有明显差异,STEMI组高于NSTEMI组,NSTEMI组高于UAP组,UAP组高于对照组.冠状动脉狭窄程度评分为(96.3±11.7)分,与hs-CRP(r=0.2764,P<0.05)、LPA(r=0.2119,P<0.05)呈正相关.结论 急性冠状动脉综合征患者血浆hs-CRP和LPA与冠状动脉的狭窄程度有明显关系.
目的 探討急性冠狀動脈綜閤徵患者血漿超敏C-反應蛋白(hs-CRP)、溶血燐脂痠(LPA)與冠狀動脈狹窄程度的相關性.方法 131例急性冠狀動脈綜閤徵患者分為ST段抬高型心肌梗死(STEMI)組41例、非ST段抬高型心肌梗死(NSTEMI)組42例、不穩型心絞痛(UAP)組48例,再選取30例健康人為對照組.所有入選者測定hs-CRP和LPA,急性冠狀動脈的患者行冠狀動脈造影判斷狹窄的程度.結果 四組間hs-CRP、LPA有明顯差異,STEMI組高于NSTEMI組,NSTEMI組高于UAP組,UAP組高于對照組.冠狀動脈狹窄程度評分為(96.3±11.7)分,與hs-CRP(r=0.2764,P<0.05)、LPA(r=0.2119,P<0.05)呈正相關.結論 急性冠狀動脈綜閤徵患者血漿hs-CRP和LPA與冠狀動脈的狹窄程度有明顯關繫.
목적 탐토급성관상동맥종합정환자혈장초민C-반응단백(hs-CRP)、용혈린지산(LPA)여관상동맥협착정도적상관성.방법 131례급성관상동맥종합정환자분위ST단태고형심기경사(STEMI)조41례、비ST단태고형심기경사(NSTEMI)조42례、불은형심교통(UAP)조48례,재선취30례건강인위대조조.소유입선자측정hs-CRP화LPA,급성관상동맥적환자행관상동맥조영판단협착적정도.결과 사조간hs-CRP、LPA유명현차이,STEMI조고우NSTEMI조,NSTEMI조고우UAP조,UAP조고우대조조.관상동맥협착정도평분위(96.3±11.7)분,여hs-CRP(r=0.2764,P<0.05)、LPA(r=0.2119,P<0.05)정정상관.결론 급성관상동맥종합정환자혈장hs-CRP화LPA여관상동맥적협착정도유명현관계.
Objective To investigate the correlationship of high sensitivity C-reactive protein (hs-CRP),lysophosphatidic acid (LPA) and coronary artery stenosis in patients with acute coronary syndrome.Methods One hundred and thirtyone patients with acute coronary syndrome were divided into ST-segment elevation myocardial infarction (STEMI) group (n =41),non-ST-segment elevation myocardial infarction (NSTEMI) group (n =42) and unstable angina(UAP) group(n =48).Thirty heathy people were enrolled into the control group.The hs-CRP and LPA were detected in all people.Coronary artery stenosis were judged in patients with acute coronary syndrome.Results As hs-CRP and LPA were compared,these of STEMI were higher than these of NSTEMI,NSTEMI higher than UAP and UAP higher than the control group.The score of Gensini was 96.3 ± 11.7,which had a positive correlation with hs-CRP(r =0.2764,P <0.05) and LPA (r =0.2119,P < 0.05).Conclusions There has a significant correlation between hsCRP,LPA and coronary artery stenosis.