CAJ | 학술논문

目的探讨首发、复发抑郁症患者血清甲状腺激素的水平变化.方法对63例首发、55例复发抑郁症患者及60例健康对照者采用电化学发光免疫分析法测定血清游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺激素(TSH)的含量.结果 ①首发与复发组血清FT3、FT4较对照组高(P＜0.01),首发与复发组血清TSH较对照组低(P＜0.01)；②复发组患者FT4高于首发组患者(P＜0.05).结论首发与复发抑郁症患者血清FT3、FT4较对照组高,TSH较对照组低；复发患者中血清FT4较首发患者高,存在更为明显的甲状腺系统代谢异常.
목적 탐토수발、복발억욱증환자혈청갑상선격소적수평변화.방법 대63례수발、55례복발억욱증환자급60례건강대조자채용전화학발광면역분석법측정혈청유리삼전갑상선원안산(FT3)、유리갑상선소(FT4)、촉갑상선격소(TSH)적함량.결과 ①수발여복발조혈청FT3、FT4교대조조고(P＜0.01),수발여복발조혈청TSH교대조조저(P＜0.01)；②복발조환자FT4고우수발조환자(P＜0.05).결론 수발여복발억욱증환자혈청FT3、FT4교대조조고,TSH교대조조저；복발환자중혈청FT4교수발환자고,존재경위명현적갑상선계통대사이상.
Objective To investigate the serum thyroid hormone changes in patients with incipient depression and recurrence depression.Methods For 63 cases of incipient depression,55 cases of recurrence depression and 60 healthy controls,using the immunochemical luminescence,the levels of FT3,FT4 and TSH were tested.Results ①The levels of FT3 and FT4 were higher in incipient depression group and recurrence depression group than those in healthy controls(P ＜0.01).The level of TSH was lower in incipient depression group and recurrence depression group than that in healthy controls (P ＜ 0.01).②The level of FT4 in recurrent depression group was higher than that in incipient depression group.Conclusions There was thyroid hormone metabolism disorder in incipient depression group and recurrence depression group.FT4 in recurrent group was higher than that in incipient group.And thyroid system metabolic abnormalities is more obvious in recurrent group.