中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
12期
28-29
,共2页
三七皂甙%静脉溶栓%急性脑梗死%作用机制
三七皂甙%靜脈溶栓%急性腦梗死%作用機製
삼칠조대%정맥용전%급성뇌경사%작용궤제
Sanchinoside%Intravenous thrombolysis%Acute cerebral infarction%Mechanism of action
目的 结合三七皂甙联合静脉溶栓治疗急性脑梗死的作用机制,观察其临床治疗效果.方法 将84例急性脑梗死患者随机分为两组,应用三七皂甙联合尿激酶静脉溶栓治疗急性脑梗死者为实验组；应用普通尿激酶静脉溶栓法治疗急性脑梗死者为对照组.经过2个疗程治疗后,比较两组的治疗效果,并比较患者治疗后神经功能的损伤程度.结果 实验组的有效率为88.1％,对照组的有效率为76.2％,实验组明显高于对照组；实验组患者轻型神经功能损伤率为57.14％,明显高于对照组,重型神经功能损伤率为14.29％,明显低于对照组,P均＜0.05.结论 应用三七皂甙联合静脉溶栓治疗急性脑梗死效果明显,三七皂甙有明显改善急性脑梗死患者缺血再灌注的作用.
目的 結閤三七皂甙聯閤靜脈溶栓治療急性腦梗死的作用機製,觀察其臨床治療效果.方法 將84例急性腦梗死患者隨機分為兩組,應用三七皂甙聯閤尿激酶靜脈溶栓治療急性腦梗死者為實驗組；應用普通尿激酶靜脈溶栓法治療急性腦梗死者為對照組.經過2箇療程治療後,比較兩組的治療效果,併比較患者治療後神經功能的損傷程度.結果 實驗組的有效率為88.1％,對照組的有效率為76.2％,實驗組明顯高于對照組；實驗組患者輕型神經功能損傷率為57.14％,明顯高于對照組,重型神經功能損傷率為14.29％,明顯低于對照組,P均＜0.05.結論 應用三七皂甙聯閤靜脈溶栓治療急性腦梗死效果明顯,三七皂甙有明顯改善急性腦梗死患者缺血再灌註的作用.
목적 결합삼칠조대연합정맥용전치료급성뇌경사적작용궤제,관찰기림상치료효과.방법 장84례급성뇌경사환자수궤분위량조,응용삼칠조대연합뇨격매정맥용전치료급성뇌경사자위실험조；응용보통뇨격매정맥용전법치료급성뇌경사자위대조조.경과2개료정치료후,비교량조적치료효과,병비교환자치료후신경공능적손상정도.결과 실험조적유효솔위88.1％,대조조적유효솔위76.2％,실험조명현고우대조조；실험조환자경형신경공능손상솔위57.14％,명현고우대조조,중형신경공능손상솔위14.29％,명현저우대조조,P균＜0.05.결론 응용삼칠조대연합정맥용전치료급성뇌경사효과명현,삼칠조대유명현개선급성뇌경사환자결혈재관주적작용.
Objective To observe the clinical curative effect of sanchinoside combined with intravenous thrombolysis in treating acute cerebral infarction according to its mechanism action.Methods To divided 84 cases of acute cerebral infarction into two groups randomly,adopting sanchinoside combined with urokinase venous thrombolysis treatment experimental group,while adopting ordinary urokinase venous thrombolysis as control group.After 2 courses of treatment,compared the efficacy of the two groups,and compared the degree of nerve injury.Results The effective rate of experimental group was 88.1％,and 76.2％ in control group,the difference was significant (P ＜ 0.05).The incidence of mild nerve injury in experimental group was significantly higher than that in control group,while the incidence of sever nerve injury in experimental group was significantly lower than that in control group,all P ＜0.05.Conclusions Sanchinoside combined with intravenous thrombolysis for acute cerebral infarction has obvious effect,and sanchinoside has the significant function of improving ischemia-reperfusion in acute cerebral infarction.
