中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
14期
87-89
,共3页
绝经前女性%冠心病%危险因素%同型半胱氨酸
絕經前女性%冠心病%危險因素%同型半胱氨痠
절경전녀성%관심병%위험인소%동형반광안산
Premenopausal women%Coronary heart disease%Risk factors%Homocysteine
目的 探讨绝经前女性冠心病患者临床危险因素的特点.方法 选择2010年10月至2012年10月已拟诊冠心病住院的绝经前女性患者140例,根据冠脉造影检查分为冠心病组(90例)和对照组(50例),对140例患者均抽血检测总胆固醇、三酰甘油、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、尿酸、C-反应蛋白、同型半胱氨酸,并详细询问患者的年龄、身高、体质量、冠心病家族史、吸烟史、高血压史及糖尿病史.结果 冠心病组中高血压史、糖尿病史、体质量指数、三酰甘油、C-反应蛋白、同型半胱氨酸均高于正常对照组,高密度脂蛋白胆固醇低于对照组；糖尿病史、高血压史、三酰甘油、同型半胱氨酸、C-反应蛋白为绝经前女性冠心病的独立危险因素,而高密度脂蛋白胆固醇为绝经前女性冠心病的保护因素.冠心病组同型半胱氨酸与三酰甘油和C-反应蛋白呈正相关,与高密度脂蛋白胆固醇呈负相关.结论 高血压、糖尿病、三酰甘油、同型半胱氨酸、C-反应蛋白为绝经前女性冠心病患者的独立危险因素.同型半胱氨酸与绝经前女性冠心痛患者其他危险因素可能具有协同作用,共同促进绝经前女性冠心病的发生、发展.
目的 探討絕經前女性冠心病患者臨床危險因素的特點.方法 選擇2010年10月至2012年10月已擬診冠心病住院的絕經前女性患者140例,根據冠脈造影檢查分為冠心病組(90例)和對照組(50例),對140例患者均抽血檢測總膽固醇、三酰甘油、高密度脂蛋白膽固醇、低密度脂蛋白膽固醇、尿痠、C-反應蛋白、同型半胱氨痠,併詳細詢問患者的年齡、身高、體質量、冠心病傢族史、吸煙史、高血壓史及糖尿病史.結果 冠心病組中高血壓史、糖尿病史、體質量指數、三酰甘油、C-反應蛋白、同型半胱氨痠均高于正常對照組,高密度脂蛋白膽固醇低于對照組；糖尿病史、高血壓史、三酰甘油、同型半胱氨痠、C-反應蛋白為絕經前女性冠心病的獨立危險因素,而高密度脂蛋白膽固醇為絕經前女性冠心病的保護因素.冠心病組同型半胱氨痠與三酰甘油和C-反應蛋白呈正相關,與高密度脂蛋白膽固醇呈負相關.結論 高血壓、糖尿病、三酰甘油、同型半胱氨痠、C-反應蛋白為絕經前女性冠心病患者的獨立危險因素.同型半胱氨痠與絕經前女性冠心痛患者其他危險因素可能具有協同作用,共同促進絕經前女性冠心病的髮生、髮展.
목적 탐토절경전녀성관심병환자림상위험인소적특점.방법 선택2010년10월지2012년10월이의진관심병주원적절경전녀성환자140례,근거관맥조영검사분위관심병조(90례)화대조조(50례),대140례환자균추혈검측총담고순、삼선감유、고밀도지단백담고순、저밀도지단백담고순、뇨산、C-반응단백、동형반광안산,병상세순문환자적년령、신고、체질량、관심병가족사、흡연사、고혈압사급당뇨병사.결과 관심병조중고혈압사、당뇨병사、체질량지수、삼선감유、C-반응단백、동형반광안산균고우정상대조조,고밀도지단백담고순저우대조조；당뇨병사、고혈압사、삼선감유、동형반광안산、C-반응단백위절경전녀성관심병적독립위험인소,이고밀도지단백담고순위절경전녀성관심병적보호인소.관심병조동형반광안산여삼선감유화C-반응단백정정상관,여고밀도지단백담고순정부상관.결론 고혈압、당뇨병、삼선감유、동형반광안산、C-반응단백위절경전녀성관심병환자적독립위험인소.동형반광안산여절경전녀성관심통환자기타위험인소가능구유협동작용,공동촉진절경전녀성관심병적발생、발전.
Objective To investigate the clinical features of the risk factors of premenopausal women with coronary heart disease(CHD).Methods From October 2010 to October 2012,140 premenopausal women patients diagnosed as coronary heart disease were included.According to the coronary angiography (CAG) result,all patients were divided into CHD group (90 patients) and control group (50 patients).All of the 140 cases were determinated the level of TC,TG,HDL-C,LDL-C,UA,CRP and HCY.Age,weight,family history of coronary heart disease,smoking history,hypertension history and diabetes history being asked in details.Results Compared with the control group,there were significant higher proportion of hypertension,diabetes,BMI and increased TG,CRP,HCY levels and decreased HDL-C level in CHD group.Multivariate Logistic regression analysis showed hypertension,diabetes,TG,CRP,HCY,and decreased HDL-C were independent risk factors for CHD group patients.The HCY level of CHD group were positively correlated with the level of TG and CRP,and negatively correlated with the level of HDL-C.Conclusions The study suggests that TG,hypertension,diabetes,CRP,HCY and lower HDL-C levels were independent risk factors for premenopausal women with coronary heart disease.HCY may have a synergistic effect with other risk factors.
