中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
16期
42-44
,共3页
肠内免疫营养%食管癌%营养状态%免疫功能%炎症反应
腸內免疫營養%食管癌%營養狀態%免疫功能%炎癥反應
장내면역영양%식관암%영양상태%면역공능%염증반응
Enteral immunonutrition%Esophageal cancer%Nutrition status%Immune function%Inflammatory reaction
目的 评价食管癌术后患者早期肠内营养对患者营养状态、免疫功能、炎症反应和感染并发症的影响.方法 将120例食管癌患者随机分为IEN组(免疫肠内营养组)和SEN组(标准肠内营养组).所有患者均于术前和术后第1、4、9天分别检测营养指标(ALB、PA、TF)、免疫指标(IgA、IgG、IgM)和炎症指标(C3、C4、CRP),并观察记录术后肠道功能恢复时间及感染性并发症的发生情况.结果 两组患者的胃肠道功能恢复时间比较差异无统计学意义,IEN组感染并发症少于SEN组.术后第9天,两组患者的营养指标比较差异无统计学意义(P＞0.05)；IEN组的IgA、IgM和IgG水平显著高于SEN组,而IEN组C4、CRP水平显著低于SEN组(P＜0.05).结论 食管癌患者术后早期应用IEN能维持营养状态、恢复免疫功能、降低全身炎症反应,可能减少术后感染的发生.
目的 評價食管癌術後患者早期腸內營養對患者營養狀態、免疫功能、炎癥反應和感染併髮癥的影響.方法 將120例食管癌患者隨機分為IEN組(免疫腸內營養組)和SEN組(標準腸內營養組).所有患者均于術前和術後第1、4、9天分彆檢測營養指標(ALB、PA、TF)、免疫指標(IgA、IgG、IgM)和炎癥指標(C3、C4、CRP),併觀察記錄術後腸道功能恢複時間及感染性併髮癥的髮生情況.結果 兩組患者的胃腸道功能恢複時間比較差異無統計學意義,IEN組感染併髮癥少于SEN組.術後第9天,兩組患者的營養指標比較差異無統計學意義(P＞0.05)；IEN組的IgA、IgM和IgG水平顯著高于SEN組,而IEN組C4、CRP水平顯著低于SEN組(P＜0.05).結論 食管癌患者術後早期應用IEN能維持營養狀態、恢複免疫功能、降低全身炎癥反應,可能減少術後感染的髮生.
목적 평개식관암술후환자조기장내영양대환자영양상태、면역공능、염증반응화감염병발증적영향.방법 장120례식관암환자수궤분위IEN조(면역장내영양조)화SEN조(표준장내영양조).소유환자균우술전화술후제1、4、9천분별검측영양지표(ALB、PA、TF)、면역지표(IgA、IgG、IgM)화염증지표(C3、C4、CRP),병관찰기록술후장도공능회복시간급감염성병발증적발생정황.결과 량조환자적위장도공능회복시간비교차이무통계학의의,IEN조감염병발증소우SEN조.술후제9천,량조환자적영양지표비교차이무통계학의의(P＞0.05)；IEN조적IgA、IgM화IgG수평현저고우SEN조,이IEN조C4、CRP수평현저저우SEN조(P＜0.05).결론 식관암환자술후조기응용IEN능유지영양상태、회복면역공능、강저전신염증반응,가능감소술후감염적발생.
Objective To evaluate the clinical effect of postoperative early enteral nutrition on nutrient status,immune function,stress status and infectious complications in patients with esophageal cancer.Methods Total 120 patients with esophageal cancer were randomly divided into two groups:IEN group(immune-enhancing enteral nutrition)and SEN group (standard enteral nutrition).The levels of nutrition status (HGB,ALB,TF),immune function (IgA,lgG,IgM) and stress status (C3,C4,CRP) were detected before operation and on postoprative 1,4,9 days.The postoperative infection and bowel function were observed.Results There was no statistic difference between the two groups on bowel function,but the postoperative infection in IEN group was less than in SEN group.On the 9th day after operation,there was no statistic difference between each group on the serum levels of nutrition index (P ＞ 0.05).The serum levels of IgA,IgM and IgG in IEN group were significantly higher than those in SEN group,while the serum levels of C4 and CRP in IEN group were significantly lower than those in SEN group (P ＜ 0.05).Conclusions The application of postoperative early IEN with esophageal cancer can maintain normal nutrition status,enhance immune function,lower systemic inflammatory reaction ir patients.
