中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
22期
4-6
,共3页
王爱霞%詹志伟%李全民%赵保明
王愛霞%詹誌偉%李全民%趙保明
왕애하%첨지위%리전민%조보명
男性%2型糖尿病%25羟基维生素D%骨密度%骨质疏松症
男性%2型糖尿病%25羥基維生素D%骨密度%骨質疏鬆癥
남성%2형당뇨병%25간기유생소D%골밀도%골질소송증
Male%Type 2 diabetes mellitus%25-hydroxyvitamin D%Bone mineral density%Osteoporosis
目的 探讨男性2型糖尿病(type 2 diabetes mellitus,T2DM)患者血清25羟基维生素D[25-(OH)D3]水平的变化,以及25-(OH) D3水平与骨密度(bone mineral density,BMD)的关系.方法 87例男性T2DM患者为病例组,均行腰椎及髋部双能X线骨密度测定,同期男性健康体检者90名为正常对照组.用酶联免疫法检测各组25-(OH) D3水平及相关临床和生化指标.比较两组25-(OH) D3的水平以及25-(OH) D3与男性病例组BMD的相关性.结果 ①病例组25-(OH) D3水平为(10±4)ng/ml,对照组为(12±4)ng/ml,T2DM组25-(OH)D3明显低于对照组(P＜0.05).②病例组骨质疏松症(osteoporosis,OP)患者25-(OH) D3为(10±3)ng/ml,无OP患者为(9±4)ng/ml,两组比较差异无统计学意义(P＞0.05).结论 男性2型糖尿病患者25-(OH) D3水平明显降低,25-(OH) D3与骨密度无明显相关性.
目的 探討男性2型糖尿病(type 2 diabetes mellitus,T2DM)患者血清25羥基維生素D[25-(OH)D3]水平的變化,以及25-(OH) D3水平與骨密度(bone mineral density,BMD)的關繫.方法 87例男性T2DM患者為病例組,均行腰椎及髖部雙能X線骨密度測定,同期男性健康體檢者90名為正常對照組.用酶聯免疫法檢測各組25-(OH) D3水平及相關臨床和生化指標.比較兩組25-(OH) D3的水平以及25-(OH) D3與男性病例組BMD的相關性.結果 ①病例組25-(OH) D3水平為(10±4)ng/ml,對照組為(12±4)ng/ml,T2DM組25-(OH)D3明顯低于對照組(P＜0.05).②病例組骨質疏鬆癥(osteoporosis,OP)患者25-(OH) D3為(10±3)ng/ml,無OP患者為(9±4)ng/ml,兩組比較差異無統計學意義(P＞0.05).結論 男性2型糖尿病患者25-(OH) D3水平明顯降低,25-(OH) D3與骨密度無明顯相關性.
목적 탐토남성2형당뇨병(type 2 diabetes mellitus,T2DM)환자혈청25간기유생소D[25-(OH)D3]수평적변화,이급25-(OH) D3수평여골밀도(bone mineral density,BMD)적관계.방법 87례남성T2DM환자위병례조,균행요추급관부쌍능X선골밀도측정,동기남성건강체검자90명위정상대조조.용매련면역법검측각조25-(OH) D3수평급상관림상화생화지표.비교량조25-(OH) D3적수평이급25-(OH) D3여남성병례조BMD적상관성.결과 ①병례조25-(OH) D3수평위(10±4)ng/ml,대조조위(12±4)ng/ml,T2DM조25-(OH)D3명현저우대조조(P＜0.05).②병례조골질소송증(osteoporosis,OP)환자25-(OH) D3위(10±3)ng/ml,무OP환자위(9±4)ng/ml,량조비교차이무통계학의의(P＞0.05).결론 남성2형당뇨병환자25-(OH) D3수평명현강저,25-(OH) D3여골밀도무명현상관성.
Objective To investigate the serum changes of 25-hydroxyvitamin D level in the male patients with type 2 diabetes,and the relationships between 25-hydroxyvitamin D level and bone mineral density.Methods Eighty-seven male patients with type 2 diabetes mellitus were selected as the case group,and 90 male healthy people were selected as the control group.ELISA were used for the detection of serum 25-hydroxyvitamin D,relevant clinical and biochemical index were also detected.Then the serum differences of 25-hydroxyvitamin D levels in the two groups were contrasted and the relationship between 25-hydroxyvitamin D and the T2DM male patients was analyzed.Results ①Serum 25-hydroxyvitamin D level of T2DM group was significantly lower than that of the control group(P ＜0.05).②There was no significant difference in serum 25-hydroxyvitamin D level between osteoporosis patients group and no osteoporosis patients group in T2DM group (P ＞ 0.05).Conclusions Serum 25-hydroxyvitamin D level in male patients with type 2 diabetes was significantly lower than that of control group.No correlation was found between serum 25-hydroxyvitamin D level and bone mineral density in male patients with type 2 diabetes.
