中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
23期
18-20
,共3页
支气管哮喘%双水平无创通气%治疗
支氣管哮喘%雙水平無創通氣%治療
지기관효천%쌍수평무창통기%치료
Bronchial asthma%Bilevel positive airway pressure (BiPAP)%Therapy
目的 对比常规治疗与常规治疗联合双水平无创通气治疗中重度支气管哮喘急性发作的临床效果.方法 选择中重度支气管哮喘急性发作期的患者32例作为研究对象,随机分为治疗组和对照组,对照组仅采用常规静脉激素应用及雾化吸入平喘药,根据情况加用抗生素,治疗组在对照组治疗的基础上联用双水平无创通气,两组均在治疗前、治疗后30 min、60 min、2h、24 h、48 h及72 h及停用无创通气1d后分别记录指脉氧饱和度、心率、呼吸频率、动脉血气分析、询问患者呼吸困难缓解情况、两肺哮鸣音减少及消失情况,无创通气仅用3d,在治疗前、治疗3d及4d后行肺功能检查,记录FEV1占预计值百分比及FVC.结果 两组患者的FEV1占预计值百分比、呼吸频率、PaCO2等指标均有改善,但治疗组在同一时间点的各项指标均明显优于对照组,且治疗组的症状、体征缓解得更快,而两组治疗后PaCO2、FVC及心率虽较治疗前均有好转,但两组间差异无统计学意义.结论 对于中重度支气管哮喘急性发作期的患者,可以在常规治疗的基础上联用双水平无创通气.
目的 對比常規治療與常規治療聯閤雙水平無創通氣治療中重度支氣管哮喘急性髮作的臨床效果.方法 選擇中重度支氣管哮喘急性髮作期的患者32例作為研究對象,隨機分為治療組和對照組,對照組僅採用常規靜脈激素應用及霧化吸入平喘藥,根據情況加用抗生素,治療組在對照組治療的基礎上聯用雙水平無創通氣,兩組均在治療前、治療後30 min、60 min、2h、24 h、48 h及72 h及停用無創通氣1d後分彆記錄指脈氧飽和度、心率、呼吸頻率、動脈血氣分析、詢問患者呼吸睏難緩解情況、兩肺哮鳴音減少及消失情況,無創通氣僅用3d,在治療前、治療3d及4d後行肺功能檢查,記錄FEV1佔預計值百分比及FVC.結果 兩組患者的FEV1佔預計值百分比、呼吸頻率、PaCO2等指標均有改善,但治療組在同一時間點的各項指標均明顯優于對照組,且治療組的癥狀、體徵緩解得更快,而兩組治療後PaCO2、FVC及心率雖較治療前均有好轉,但兩組間差異無統計學意義.結論 對于中重度支氣管哮喘急性髮作期的患者,可以在常規治療的基礎上聯用雙水平無創通氣.
목적 대비상규치료여상규치료연합쌍수평무창통기치료중중도지기관효천급성발작적림상효과.방법 선택중중도지기관효천급성발작기적환자32례작위연구대상,수궤분위치료조화대조조,대조조부채용상규정맥격소응용급무화흡입평천약,근거정황가용항생소,치료조재대조조치료적기출상련용쌍수평무창통기,량조균재치료전、치료후30 min、60 min、2h、24 h、48 h급72 h급정용무창통기1d후분별기록지맥양포화도、심솔、호흡빈솔、동맥혈기분석、순문환자호흡곤난완해정황、량폐효명음감소급소실정황,무창통기부용3d,재치료전、치료3d급4d후행폐공능검사,기록FEV1점예계치백분비급FVC.결과 량조환자적FEV1점예계치백분비、호흡빈솔、PaCO2등지표균유개선,단치료조재동일시간점적각항지표균명현우우대조조,차치료조적증상、체정완해득경쾌,이량조치료후PaCO2、FVC급심솔수교치료전균유호전,단량조간차이무통계학의의.결론 대우중중도지기관효천급성발작기적환자,가이재상규치료적기출상련용쌍수평무창통기.
Objective To compare the different effects of conventional therapy and BiPAP plus conventional therapy on patients with acute moderate or serious bronchial asthma.Methods Thirty-two cases of moderate or serious bronchial asthma in acute stage were chose.Sixteen patients were given BiPAP plus conventional therapy and 16 patients were given conventional therapy alone.Both groups had similar clinical characteristics on hospital admission.Bedside lung function test results and vital signs,such as SaO2,HR,RR,PaO2,PaCO2,were obtained at baseline,and during at 30 min,1 h,2 h,24 h,48 h,72 h and at the end and one day after the study protocol.At the third and fourth day,lung function and record FEV1,FVC were examined.Results After 3 days ventilation,the levels of FEV1,PaCO2 and breath rate of the two groups all improved,but the BiPAP group was superior to control group in each indexes at the given time,and the time of dyspnea alleviation and dispearance were shorter significantly in BiPAP group.So most patients avoided invasive ventilation.Conclusions It is effective to treat the patients of bronchial asthma by BiPAP plus conventional therapy.
