CAJ | 학술논문

目的探讨骨创伤后深静脉血栓(DVT)的形成与抗心磷脂抗体(ACA)以及C-反应蛋白(CRP)的关系.方法选择创伤骨折患者196例,经彩色多普勒确诊的DVT患者23例.健康查体者116例作为对照组.ELISA法检测抗心磷脂抗体,速率散射比浊法检测C-反应蛋白.结果创伤骨折患者CRP含量显著增高,但低于深静脉血栓患者;深静脉血栓患者ACA阳性率明显增高,5例ACA阳性的骨创伤患者均发生DVT;下肢骨折组、多发骨折组、骨盆骨折组CRP阳性率又高于上肢骨折组(P＜0.05).结论 ACA和CRP与骨创伤后DVT的发生相关,ACA是发生DVT的独立危险因素.
목적 탐토골창상후심정맥혈전(DVT)적형성여항심린지항체(ACA)이급C-반응단백(CRP)적관계.방법 선택창상골절환자196례,경채색다보륵학진적DVT환자23례.건강사체자116례작위대조조.ELISA법검측항심린지항체,속솔산사비탁법검측C-반응단백.결과 창상골절환자CRP함량현저증고,단저우심정맥혈전환자;심정맥혈전환자ACA양성솔명현증고,5례ACA양성적골창상환자균발생DVT;하지골절조、다발골절조、골분골절조CRP양성솔우고우상지골절조(P＜0.05).결론 ACA화CRP여골창상후DVT적발생상관,ACA시발생DVT적독립위험인소.
Objective To investigate the relationship among anticardiolipin antibodies (ACA),C-reactive protein (CRP) and deep vein thrombosis after skeletal trauma.Methods One hundred and ninety-six patients with skeletal trauma were chosen for the study,23 cases of which were definitely diagnosed by color Doppler.One hundred and sixteen healthy subjects were chose as control group.The level of anticardiolipin antibodies was assayed by enzyme linked immunoabsorbent assay (ELISA),and CRP was determined by rate nephelometry.Results CRP levels in patients with skeletal trauma were significantly high,but lower than in patients with deep venous thrombosis ; Positive rate of ACA in patients with deep vein thrombosis was significantly higher,five cases of ACA-positive skeletal trauma patients suffered from DVT; Positive rate of CRP in lower extremity fractures,multiple fractures group or pelvic fracture group was significantly higher than that in the upper limb fracture group (P ＜ 0.05).Conclusions ACA and CRP may be associated with skeletal trauma; ACA is an independent risk factor for DVT.