CAJ | 학술논문

目的探讨非高密度脂蛋白胆固醇与冠状动脉支架内再狭窄及病变加重的关系.方法总结郑州大学第一附属医院成功行经皮冠状动脉介入治疗术后12个月回院复查冠状动脉造影的226例患者的临床资料,并分为进展组(冠状动脉支架内再狭窄及冠状动脉粥样硬化病变加重)和稳定组(无支架内再狭窄及无其他冠状动脉病变加重者),对两组介入前及回院复查时的血脂指标分别进行回顾性研究分析.结果进展组54例(冠状动脉支架内再狭窄及冠状动脉粥样硬化病变加重),稳定组172例(无支架内再狭窄及无其他冠状动脉病变加重),对复查时两组的总胆固醇、低密度脂蛋白胆固醇及非高密度脂蛋白胆固醇进行比较及统计学分析,三者差异均有统计学意义.结论总胆固醇、低密度脂蛋白胆固醇及非高密度脂蛋白胆固醇是冠状动脉支架内再狭窄及未行介入治疗的其他冠状动脉管腔狭窄加重的重要危险因素,后者的预测价值优于前两者.
목적 탐토비고밀도지단백담고순여관상동맥지가내재협착급병변가중적관계.방법 총결정주대학제일부속의원성공행경피관상동맥개입치료술후12개월회원복사관상동맥조영적226례환자적림상자료,병분위진전조(관상동맥지가내재협착급관상동맥죽양경화병변가중)화은정조(무지가내재협착급무기타관상동맥병변가중자),대량조개입전급회원복사시적혈지지표분별진행회고성연구분석.결과 진전조54례(관상동맥지가내재협착급관상동맥죽양경화병변가중),은정조172례(무지가내재협착급무기타관상동맥병변가중),대복사시량조적총담고순、저밀도지단백담고순급비고밀도지단백담고순진행비교급통계학분석,삼자차이균유통계학의의.결론 총담고순、저밀도지단백담고순급비고밀도지단백담고순시관상동맥지가내재협착급미행개입치료적기타관상동맥관강협착가중적중요위험인소,후자적예측개치우우전량자.
Objective To study the relationships between non-high-density lipoprotein cholesterol and coronary in-stent restenosis,deterioration of atherosclerotic plaques.Methods The clinical data of 226 patients with coronary heart disease,who were treated by percutaneous coronary intervention (PCI),were sunmarized.After 12 months,the patients were reviewed by the coronary angiography,and they were divided into two groups:lesions progress group(coronary in-stent restenosis and deterioration of atherosclerotic plaques),no lesions progress group(no coronary in-stent restenosis or deterioration of atherosclerotic plaques).Results Among all the 226 patients,54 cases were diagnosed as coronary in-stent restenosis and deterioration of atherosclerotic plaques,172 cases without lesions progress.There were significant differences in total cholesterol (TC),low-density lipoprotein cholesterol (LDL-C),and non-high-density lipoprotein cholesterol (non-HDL-C) between the two groups.Conclusions TC,LDL-C,non-HDL-C may be important risk factors for the coronary stent restenosis after PCI,but the predictive value of non-HDL-C is superior to TC or LDL-C.