中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2014年
7期
53-55
,共3页
原始神经外胚层肿瘤%治疗%预后
原始神經外胚層腫瘤%治療%預後
원시신경외배층종류%치료%예후
Primitive neuroectodermal tumors%Therapy%Prognosis
目的 探讨儿童原始神经外胚层肿瘤(PNET)的临床表现、病理学特征、治疗及预后.方法 回顾性分析郑州大学第一附属医院16例PNET患儿的临床资料,采用Kaplan-Meier法计算生存率.结果 16例患儿中14例死亡,中位生存期为22个月,6例单纯手术切除组及10例术后放、化疗组的中位生存期分别为13、28个月,两组比较差异有统计学意义(P＜0.05).结论 PNET是一种高度恶性肿瘤,好发于青少年,预后较差,综合治疗是原始神经外胚层瘤的主要治疗方法,其生存期要优于非综合治疗组.
目的 探討兒童原始神經外胚層腫瘤(PNET)的臨床錶現、病理學特徵、治療及預後.方法 迴顧性分析鄭州大學第一附屬醫院16例PNET患兒的臨床資料,採用Kaplan-Meier法計算生存率.結果 16例患兒中14例死亡,中位生存期為22箇月,6例單純手術切除組及10例術後放、化療組的中位生存期分彆為13、28箇月,兩組比較差異有統計學意義(P＜0.05).結論 PNET是一種高度噁性腫瘤,好髮于青少年,預後較差,綜閤治療是原始神經外胚層瘤的主要治療方法,其生存期要優于非綜閤治療組.
목적 탐토인동원시신경외배층종류(PNET)적림상표현、병이학특정、치료급예후.방법 회고성분석정주대학제일부속의원16례PNET환인적림상자료,채용Kaplan-Meier법계산생존솔.결과 16례환인중14례사망,중위생존기위22개월,6례단순수술절제조급10례술후방、화료조적중위생존기분별위13、28개월,량조비교차이유통계학의의(P＜0.05).결론 PNET시일충고도악성종류,호발우청소년,예후교차,종합치료시원시신경외배층류적주요치료방법,기생존기요우우비종합치료조.
Objective To investigate the clinical and pathological features,therapy and prognosis of primitive neuroectodermal tumors(PNET) in children.Methods The clinical data of 16 children with PNET were analyzed retrospectively.The survival rate was calculated by Kaplan-Meier.Results Among the 16 children,14 children died.The median survival time was 22 months.The median survival time was 13 months for group S (surgical resection alone) and 28 months for group S + R + C (chemotherapy plus radiotherapy after surgery),respectively.There were significant differences between the two groups (P ＜ 0.05).Conclusions PNET,a highly malignant tumor,most often occurs in young people,and the prognosis is poor.The combined therapy is the main treatment for PNET,and the survival time of the combined therapy group is longer than that of the non-combined therapy group.
