中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2014年
7期
72-74
,共3页
贫血%低蛋白血症%慢性心力衰竭%危险因素
貧血%低蛋白血癥%慢性心力衰竭%危險因素
빈혈%저단백혈증%만성심력쇠갈%위험인소
Anemia%Hypoproteinemia%Chronic heart failure%Risk factors
目的 观察和分析贫血及低蛋白血症对慢性心力衰竭(CHF)患者预后的影响.方法 选取117例首诊CHF患者作为研究对象,于入院时对其血红蛋白(Hb)、血白蛋白(Alb)、前白蛋白(PA)、铁蛋白(Fer)、总铁结合力(TIBC)进行检测和记录,根据患者出院1年后的生存情况将其分为存活组和死亡组,对两组患者的上述观察指标进行比较,并分析患者发生死亡与上述指标的关系.结果 出院后1年,纳入患者中有87例存活,占74.4%,有30例患者死亡,占25.6%,其中,存活组的男性患者比例显著低于死亡组(P<0.05),存活组的年龄显著小于死亡组(P<0.05);存活组患者的Hb、Alb、PA水平显著高于死亡组(P<0.05),两组在Fer、TIBC水平方面比较差异无统计学意义(P>0.05);多元回归结果显示,患者Hb、Alb、PA水平与患者发生死亡呈负相关(P<0.05,OR值分别为0.617、0.964、0.528),而患者年龄和性别为男性与患者发生死亡呈正相关(P<0.05,OR值分别为1.738、1.317).结论 CHF患者出院后1年病死率较高,Hb、Alb、PA水平是CHF患者发生死亡的保护因素,而年龄和性别为男性则是CHF患者发生死亡的危险因素,临床医生应根据相关因素制定相应的治疗方案.
目的 觀察和分析貧血及低蛋白血癥對慢性心力衰竭(CHF)患者預後的影響.方法 選取117例首診CHF患者作為研究對象,于入院時對其血紅蛋白(Hb)、血白蛋白(Alb)、前白蛋白(PA)、鐵蛋白(Fer)、總鐵結閤力(TIBC)進行檢測和記錄,根據患者齣院1年後的生存情況將其分為存活組和死亡組,對兩組患者的上述觀察指標進行比較,併分析患者髮生死亡與上述指標的關繫.結果 齣院後1年,納入患者中有87例存活,佔74.4%,有30例患者死亡,佔25.6%,其中,存活組的男性患者比例顯著低于死亡組(P<0.05),存活組的年齡顯著小于死亡組(P<0.05);存活組患者的Hb、Alb、PA水平顯著高于死亡組(P<0.05),兩組在Fer、TIBC水平方麵比較差異無統計學意義(P>0.05);多元迴歸結果顯示,患者Hb、Alb、PA水平與患者髮生死亡呈負相關(P<0.05,OR值分彆為0.617、0.964、0.528),而患者年齡和性彆為男性與患者髮生死亡呈正相關(P<0.05,OR值分彆為1.738、1.317).結論 CHF患者齣院後1年病死率較高,Hb、Alb、PA水平是CHF患者髮生死亡的保護因素,而年齡和性彆為男性則是CHF患者髮生死亡的危險因素,臨床醫生應根據相關因素製定相應的治療方案.
목적 관찰화분석빈혈급저단백혈증대만성심력쇠갈(CHF)환자예후적영향.방법 선취117례수진CHF환자작위연구대상,우입원시대기혈홍단백(Hb)、혈백단백(Alb)、전백단백(PA)、철단백(Fer)、총철결합력(TIBC)진행검측화기록,근거환자출원1년후적생존정황장기분위존활조화사망조,대량조환자적상술관찰지표진행비교,병분석환자발생사망여상술지표적관계.결과 출원후1년,납입환자중유87례존활,점74.4%,유30례환자사망,점25.6%,기중,존활조적남성환자비례현저저우사망조(P<0.05),존활조적년령현저소우사망조(P<0.05);존활조환자적Hb、Alb、PA수평현저고우사망조(P<0.05),량조재Fer、TIBC수평방면비교차이무통계학의의(P>0.05);다원회귀결과현시,환자Hb、Alb、PA수평여환자발생사망정부상관(P<0.05,OR치분별위0.617、0.964、0.528),이환자년령화성별위남성여환자발생사망정정상관(P<0.05,OR치분별위1.738、1.317).결론 CHF환자출원후1년병사솔교고,Hb、Alb、PA수평시CHF환자발생사망적보호인소,이년령화성별위남성칙시CHF환자발생사망적위험인소,림상의생응근거상관인소제정상응적치료방안.
Objective To observe and analyze the effects of anemia and hypoproteinemia on prognosis of patients with chronic heart failure (CHF).Methods One hundred and seventeen CHF patients were selected as the research objects.On the admission day,the hemoglobin (Hb),serum albumin (Alb),prealbumin (PA),serum ferritin (Fer),total iron binding capacity (TIBC) levels of the patients were detected and recorded.The patients were divided into the survival group and the death group according to their survival situation at 1 year after discharged day.The indexes of the patients in the two groups were compared and observed and the relationship between the indexes and the death of the patients were analyzed.Results One year after discharged day,87 patients enrolled survived,accounting for 74.4%,30 patients died,accounting for 25.6%.Among them,the proportion of male patients in the survival group was significantly lower than that in the death group (P < 0.05).The age of the patients in the survival group was significantly less than that in the death group (P < 0.05) ; the Hb,Alb,PA levels of the patients in the survival group were significantly higher than those in the death group (P < 0.05),and the differences in Fer,TIBC levels between the two groups were not significant (P > 0.05); multiple regression showed that the death was negatively correlated with Hb,Alb,PA levels of the patients (P < 0.05,OR =0.617,0.964,0.528),and the patient' s age and male were positively correlated with the death of the patients (P <0.05,OR =1.738,1.317).Conclusions The mortality of CHF patients at 1 year after discharge is high.The Hb,Alb,PA levels were protective factors from death of patients with CHF,while age and male are the risk factors in death of patients with CHF.The clinicians should make the corresponding treatment plan according to the related factors.