中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2014年
9期
46-48
,共3页
血培养%凝固酶阴性葡萄球菌%临床价值
血培養%凝固酶陰性葡萄毬菌%臨床價值
혈배양%응고매음성포도구균%림상개치
Blood culture%Coagulase negative staphylococcus%Clinical value
目的 探讨血培养中凝固酶阴性葡萄球菌的临床价值.方法 回顾性分析86例血培养CNS阳性患者的临床资料、CNS检测时间、药敏结果以及患者治疗情况,分析其临床意义.结果 CNS感染所致菌血症42例(48.8％),污染菌44例(51.2％);污染菌检出时间显著长于病原菌检出时间(P＜0.01);病原菌与污染菌对头孢西丁、青霉素、头孢呋辛、头孢唑林、庆大霉素、万古霉素、环丙沙星等抗菌药物耐药性比较差异均无统计学意义(P＞0.05),对万古霉素均敏感;42例感染患者经治疗均得以控制.结论 血培养中检出CNS需根据实验室及相应临床资料区分致病菌或污染菌,虽然万古霉素为CNS敏感抗生素,但仍应避免长期大剂量应用,以避免耐药菌株的产生.
目的 探討血培養中凝固酶陰性葡萄毬菌的臨床價值.方法 迴顧性分析86例血培養CNS暘性患者的臨床資料、CNS檢測時間、藥敏結果以及患者治療情況,分析其臨床意義.結果 CNS感染所緻菌血癥42例(48.8％),汙染菌44例(51.2％);汙染菌檢齣時間顯著長于病原菌檢齣時間(P＜0.01);病原菌與汙染菌對頭孢西丁、青黴素、頭孢呋辛、頭孢唑林、慶大黴素、萬古黴素、環丙沙星等抗菌藥物耐藥性比較差異均無統計學意義(P＞0.05),對萬古黴素均敏感;42例感染患者經治療均得以控製.結論 血培養中檢齣CNS需根據實驗室及相應臨床資料區分緻病菌或汙染菌,雖然萬古黴素為CNS敏感抗生素,但仍應避免長期大劑量應用,以避免耐藥菌株的產生.
목적 탐토혈배양중응고매음성포도구균적림상개치.방법 회고성분석86례혈배양CNS양성환자적림상자료、CNS검측시간、약민결과이급환자치료정황,분석기림상의의.결과 CNS감염소치균혈증42례(48.8％),오염균44례(51.2％);오염균검출시간현저장우병원균검출시간(P＜0.01);병원균여오염균대두포서정、청매소、두포부신、두포서림、경대매소、만고매소、배병사성등항균약물내약성비교차이균무통계학의의(P＞0.05),대만고매소균민감;42례감염환자경치료균득이공제.결론 혈배양중검출CNS수근거실험실급상응림상자료구분치병균혹오염균,수연만고매소위CNS민감항생소,단잉응피면장기대제량응용,이피면내약균주적산생.
Objective To investigate the clinical value of coagulase-negative staphylococci (CNS) in blood culture.Methods The clinical data,CNS detection time,susceptibility results and treatment outcome of 86 patients with positive blood cultures CNS were retrospective analyzed,and the clinical value was analyzed.Results There were 42 patients(48.8％) with bacteremia caused by CNS infection,and 44 cases(51.2％) with contaminating bacteria; contaminating bacteria detection time was significantly longer than pathogens (P ＜ 0.01).There was no significantly difference in resistance to bacteria cefoxitin,penicillin,cefuroxime,cefazolin,gentamicin,vancomycin,ciprofloxacin between pathogenic bacteria and contaminating (P ＞ 0.05),and they were susceptible to vancomycin; 42 patients with infection were under control.Conclusions Identification of pathogenic bacteria and contaminating CNS detected in blood culture should be based on laboratory and clinical data corresponding,although CNS is sensitive to vancomycin antibiotics,but should avoid long-term and high-dose application in order to avoid drug-resistant strains.
