中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2014年
9期
54-56
,共3页
小儿%川崎病%临床分析
小兒%川崎病%臨床分析
소인%천기병%림상분석
Infant%Kawasaki disease%Clinical analysis
目的 探讨小儿川崎病(KD)的诊断及治疗方法.方法 对52例KD患儿的临床表现、辅助检查及治疗方法和治疗效果进行回顾性分析.综合性治疗基础上,治疗组(26例)应用丙种球蛋白静脉滴注(IVIG)连续治疗2次,对照组(26例)应用IVIG治疗1次.IVIG治疗无效的患儿应用糖皮质激素治疗.结果 小儿KD的诊断主要靠临床表现;治疗组总有效率为92.3％,对照组为69.2％,两组比较差异有统计学意义(P＜0.05);治疗组冠状动脉病变率为0,对照组为19.2％,两组比较差异有统计学意义(P ＜0.05);IVIG治疗无效的患儿加用糖皮质激素可缩短发热时间.结论 联合应用IVIG和阿司匹林口服是小儿KD的首选治疗方案;IVIG连续应用2次疗效显著,可明显降低冠状动脉病变率;IVIG治疗无效的患儿加用糖皮质激素有一定的疗效.
目的 探討小兒川崎病(KD)的診斷及治療方法.方法 對52例KD患兒的臨床錶現、輔助檢查及治療方法和治療效果進行迴顧性分析.綜閤性治療基礎上,治療組(26例)應用丙種毬蛋白靜脈滴註(IVIG)連續治療2次,對照組(26例)應用IVIG治療1次.IVIG治療無效的患兒應用糖皮質激素治療.結果 小兒KD的診斷主要靠臨床錶現;治療組總有效率為92.3％,對照組為69.2％,兩組比較差異有統計學意義(P＜0.05);治療組冠狀動脈病變率為0,對照組為19.2％,兩組比較差異有統計學意義(P ＜0.05);IVIG治療無效的患兒加用糖皮質激素可縮短髮熱時間.結論 聯閤應用IVIG和阿司匹林口服是小兒KD的首選治療方案;IVIG連續應用2次療效顯著,可明顯降低冠狀動脈病變率;IVIG治療無效的患兒加用糖皮質激素有一定的療效.
목적 탐토소인천기병(KD)적진단급치료방법.방법 대52례KD환인적림상표현、보조검사급치료방법화치료효과진행회고성분석.종합성치료기출상,치료조(26례)응용병충구단백정맥적주(IVIG)련속치료2차,대조조(26례)응용IVIG치료1차.IVIG치료무효적환인응용당피질격소치료.결과 소인KD적진단주요고림상표현;치료조총유효솔위92.3％,대조조위69.2％,량조비교차이유통계학의의(P＜0.05);치료조관상동맥병변솔위0,대조조위19.2％,량조비교차이유통계학의의(P ＜0.05);IVIG치료무효적환인가용당피질격소가축단발열시간.결론 연합응용IVIG화아사필림구복시소인KD적수선치료방안;IVIG련속응용2차료효현저,가명현강저관상동맥병변솔;IVIG치료무효적환인가용당피질격소유일정적료효.
Objective To investigate the diagnosis and treatment of children with Kawasaki disease(KD).Methods The clinical manifestation,auxiliary examination,treatment methods and treatment effects of 52 children with KD were retrospectively analyzed.On the basis of comprehensive treatment,the patients in treatment group (26 cases) were treated with intravenous gamma globulin (IVIG)for 2 consecutive times,and the patients in control group (26 cases) were given IVIG for 1 time.The invalid children of IVIG were treated with glucocorticoid.Results The diagnosis of children with KD depended on clinical manifestations;The total effective rate in the treatment group was 92.3％,and that in the control group was 69.2％,there was significant difference(P ＜0.05) ; Rate of coronary artery lesions in the treatment group was 0,and that in the control group was 19.2％,there was significant difference(P ＜0.05) ;The invalid children of IVIG with giucocorticoid could shorten the heating time.Conclusions Combined use of IVIG and oral aspirin is the preferred treatment method for children with KD;the curative effect of IVIG for 2 consecutive times is distinct,which can obviously reduce the rate of coronary artery lesions;the invalid children of IVIG with glucocorticoid has certain curative effect.
