中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2014年
10期
32-33
,共2页
支气管扩张%红霉素%急性加重
支氣管擴張%紅黴素%急性加重
지기관확장%홍매소%급성가중
Bronchiectasis%Erythromyci%Exacerbation
目的 观察长期口服小剂量红霉素对支气管扩张症稳定期的临床疗效.方法 38例门诊或住院治疗确诊为支气管扩张症的患者,在急性发作期积极治疗,病情稳定出院后随机分为实验组和对照组,每组22例.实验组给予口服氨溴索30 mg,,每日3次,红霉素0.125 mg,每日3次,疗程6个月.对照组仅给予口服氨溴索30 mg,每日3次,疗程6个月.结果 治疗期间,治疗组人均急性加重(0.85±0.08)次,较对照组人均急性加重次数[(1.78±0.06)次]明显减少(P＜0.05).治疗10周后,治疗组人均痰量为(29.50±6.49) ml/d,较对照组人均痰量[(55.59±11.24) ml/d]明显减少(P＜0.05).结论 长期口服小剂量红霉素可减少支气管扩张稳定期的急性发作次数,改善临床症状,减少痰量.
目的 觀察長期口服小劑量紅黴素對支氣管擴張癥穩定期的臨床療效.方法 38例門診或住院治療確診為支氣管擴張癥的患者,在急性髮作期積極治療,病情穩定齣院後隨機分為實驗組和對照組,每組22例.實驗組給予口服氨溴索30 mg,,每日3次,紅黴素0.125 mg,每日3次,療程6箇月.對照組僅給予口服氨溴索30 mg,每日3次,療程6箇月.結果 治療期間,治療組人均急性加重(0.85±0.08)次,較對照組人均急性加重次數[(1.78±0.06)次]明顯減少(P＜0.05).治療10週後,治療組人均痰量為(29.50±6.49) ml/d,較對照組人均痰量[(55.59±11.24) ml/d]明顯減少(P＜0.05).結論 長期口服小劑量紅黴素可減少支氣管擴張穩定期的急性髮作次數,改善臨床癥狀,減少痰量.
목적 관찰장기구복소제량홍매소대지기관확장증은정기적림상료효.방법 38례문진혹주원치료학진위지기관확장증적환자,재급성발작기적겁치료,병정은정출원후수궤분위실험조화대조조,매조22례.실험조급여구복안추색30 mg,,매일3차,홍매소0.125 mg,매일3차,료정6개월.대조조부급여구복안추색30 mg,매일3차,료정6개월.결과 치료기간,치료조인균급성가중(0.85±0.08)차,교대조조인균급성가중차수[(1.78±0.06)차]명현감소(P＜0.05).치료10주후,치료조인균담량위(29.50±6.49) ml/d,교대조조인균담량[(55.59±11.24) ml/d]명현감소(P＜0.05).결론 장기구복소제량홍매소가감소지기관확장은정기적급성발작차수,개선림상증상,감소담량.
Objective To observe the clinical curative effect of long-term low-dose oral nerythromyci on the patients with bronchiectasis at stationary phase.Methods Thirty-eight outpatients or inpatients that were diagnosed as bronchiectasis,were given active treatment at the acute episodes.And after they were in a stable condition and discharged,they were randomly divided into experimental group and control group,with 22 patients in each group.Patients in experimental group were given oral ammonia bromine (30 mg,3 times per day) and erythromycin (0.125 mg,3 times per day),the course was 6 months.And patients in control group were only given oral ammonia bromine (30 mg,3 times per day),the course was 6 months.Results During the treatment,the number of acute exacerbations per capita was (0.85 ± 0.08) times in the treatment group,which was significantly reduced when compared to that of the control group[(1.78 ± 0.06) times] (P ＜ 0.05).Ten weeks after the treatment,sputum volume per capita in the treatment group was (29.50 ± 6.49) ml/d,which was significantly reduced when compared to that of the control group [(55.59 ± 11.24) ml/d] (P ＜ 0.05).Conclusions Long-term lowdose oral erythromycin can reduce the number of acute exacerbations of bronchiectasis at stationary phase,thus improve the clinical symptoms and decrease sputum volume.
