中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2014年
21期
11-13
,共3页
银杏达莫%洛伐他汀%急性脑梗死%血浆黏度%全血黏度%血脂水平
銀杏達莫%洛伐他汀%急性腦梗死%血漿黏度%全血黏度%血脂水平
은행체막%락벌타정%급성뇌경사%혈장점도%전혈점도%혈지수평
Yinxingdamo%Lovastatin%Acute cerebral infarction%Plasma viscosity%Whole blood viscosity%Lipid levels
目的 研究银杏达莫(YXDM)与洛伐他汀(LOV)联用对急性脑梗死(ACI)患者的疗效及治疗后病残程度与脂质水平的相关性.方法 选择入院就诊的122例ACI患者作为观察对象.随机分两组,对照组只给予YXDM治疗,观察组给予YXDM +LOV治疗.对比两组患者全血黏度和血浆黏度,以及总胆固醇(TC)和三酰甘油(TG)水平,高密度脂蛋白胆固醇(HDL-C)及低密度脂蛋白胆固醇(LDL-C)等指标水平.对比两组疗效,并分析治疗后病残程度与脂质水平的相关性.结果 两组治疗后全血、血浆黏度均明显下降,且观察组全血黏度下降程度大于对照组;观察组治疗后TC、TG以及LDL-C水平均明显低于治疗前以及对照组在治疗后的水平,HDL-C水平高于治疗前以及对照组在治疗后的水平;观察组的总有效率显著高于对照组;差异均有统计学意义(均P＜0.05).根据Spearman法分析后发现,患者治疗后的病残程度越高,TC、TG及LDL-C水平越高,均呈正相关(r=0.857,0.832,0.794;P =0.004,0.012,0.003),但HDL-C水平越低,呈负相关(r=-0.842,P=0.010)结论 YXDM联合LOV治疗ACI疗效显著,值得推荐.
目的 研究銀杏達莫(YXDM)與洛伐他汀(LOV)聯用對急性腦梗死(ACI)患者的療效及治療後病殘程度與脂質水平的相關性.方法 選擇入院就診的122例ACI患者作為觀察對象.隨機分兩組,對照組隻給予YXDM治療,觀察組給予YXDM +LOV治療.對比兩組患者全血黏度和血漿黏度,以及總膽固醇(TC)和三酰甘油(TG)水平,高密度脂蛋白膽固醇(HDL-C)及低密度脂蛋白膽固醇(LDL-C)等指標水平.對比兩組療效,併分析治療後病殘程度與脂質水平的相關性.結果 兩組治療後全血、血漿黏度均明顯下降,且觀察組全血黏度下降程度大于對照組;觀察組治療後TC、TG以及LDL-C水平均明顯低于治療前以及對照組在治療後的水平,HDL-C水平高于治療前以及對照組在治療後的水平;觀察組的總有效率顯著高于對照組;差異均有統計學意義(均P＜0.05).根據Spearman法分析後髮現,患者治療後的病殘程度越高,TC、TG及LDL-C水平越高,均呈正相關(r=0.857,0.832,0.794;P =0.004,0.012,0.003),但HDL-C水平越低,呈負相關(r=-0.842,P=0.010)結論 YXDM聯閤LOV治療ACI療效顯著,值得推薦.
목적 연구은행체막(YXDM)여락벌타정(LOV)련용대급성뇌경사(ACI)환자적료효급치료후병잔정도여지질수평적상관성.방법 선택입원취진적122례ACI환자작위관찰대상.수궤분량조,대조조지급여YXDM치료,관찰조급여YXDM +LOV치료.대비량조환자전혈점도화혈장점도,이급총담고순(TC)화삼선감유(TG)수평,고밀도지단백담고순(HDL-C)급저밀도지단백담고순(LDL-C)등지표수평.대비량조료효,병분석치료후병잔정도여지질수평적상관성.결과 량조치료후전혈、혈장점도균명현하강,차관찰조전혈점도하강정도대우대조조;관찰조치료후TC、TG이급LDL-C수평균명현저우치료전이급대조조재치료후적수평,HDL-C수평고우치료전이급대조조재치료후적수평;관찰조적총유효솔현저고우대조조;차이균유통계학의의(균P＜0.05).근거Spearman법분석후발현,환자치료후적병잔정도월고,TC、TG급LDL-C수평월고,균정정상관(r=0.857,0.832,0.794;P =0.004,0.012,0.003),단HDL-C수평월저,정부상관(r=-0.842,P=0.010)결론 YXDM연합LOV치료ACI료효현저,치득추천.
Objective To study the curative effect of Yinxingdamo and lovastatin on acute cerebral infarction and correlation of disabled degree after treatment with lipid levels.Methods All 122 acute cerebral infarction patients were randomly divided into two groups.The control group was treated with Yinxingdamo(YXDM),the observation group was treated with YXDM and LOV.The whole blood viscosity,plasma viscosity,changes of TC,TG,HDL-C and LDL-C levels,curative effect of the two groups were compared,and the correlation of disabled degree after treatment with lipid levels were analyzed.Results Both groups after treatment of whole blood,plasma viscosity decreased significantly,and the whole blood viscosity decreased in the observation group than that in the control group.The TC,TG and LDL-C levels in the observation group after treatment were lower than those before treatment and the control group after treatment; HDL-C of the control group after treatment were higher than those before treatment.Total effective rate of the observation group was higher than that of the control group.The differences were statistically significant (P ＜ 0.05).According to Spearman method analysis,the higher the degree of disability of patients after treatment was,the higher TC,TG and LDL-C levels respectively were,which were positively correlated (r =0.857,0.832,0.794; P =0.004,0.012,0.003),however,HDL-C was lower,which were negatively correlated (r =-0.842,P =0.010).Conclusions Yinxingdamo combined with lovastatin has good effect on patients with acute cerebral infarction.It is worthy to be recommended.
