中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
13期
32-34
,共3页
谢芳%周立晓%韩定英%邹超英%吴洁%李鸿敏%刘小英%李玉梅
謝芳%週立曉%韓定英%鄒超英%吳潔%李鴻敏%劉小英%李玉梅
사방%주립효%한정영%추초영%오길%리홍민%류소영%리옥매
人乳头瘤病毒%液基细胞学检查%阴道镜%宫颈上皮内瘤变%宫颈癌%筛查
人乳頭瘤病毒%液基細胞學檢查%陰道鏡%宮頸上皮內瘤變%宮頸癌%篩查
인유두류병독%액기세포학검사%음도경%궁경상피내류변%궁경암%사사
Human papillomavirus%Liquid-based cytology test%Colposcopy%Cervical intraepithelial neoplasia%Cervical cancer%Screening
目的 了解深圳市罗湖社区已婚育龄妇女人乳头瘤病毒(HPV)感染的流行状况,探讨HPV检测在宫颈病变筛查中的临床应用价值.方法 应用多聚合酶链反应(PCR-MS) HPV分型检测方法,对1002例已婚妇女进行下生殖道HPV型别检测,对其中阳性病例行液基细胞学检查(LCT)检查,对LCT结果为意义不明的不典型鳞状细胞(ASCUS)及以上的病例行阴道镜下活检病理组织学确诊.结果 HPV检测阳性61例,阳性率为6.09％,HPV型别以HPV 16、58、18、6、51、52、66型为主.LCT结果为ASCUS及以上的病例28例,阴道镜下活检确诊宫颈上皮内瘤变(CIN)Ⅰ 8例,CINⅡ2例,CINⅢ3例,宫颈早期浸润癌1例.结论 ①深圳市罗湖社区已婚妇女中有6.09％存在HPV感染,HPV型别以16、58、18、6、51、52、66型较为多见.②HPV联合LCT检查及阴道镜下活检,能有效检出宫颈病变病例,这对宫颈上皮内瘤变及宫颈癌的早期诊治具有重要临床应用价值.
目的 瞭解深圳市囉湖社區已婚育齡婦女人乳頭瘤病毒(HPV)感染的流行狀況,探討HPV檢測在宮頸病變篩查中的臨床應用價值.方法 應用多聚閤酶鏈反應(PCR-MS) HPV分型檢測方法,對1002例已婚婦女進行下生殖道HPV型彆檢測,對其中暘性病例行液基細胞學檢查(LCT)檢查,對LCT結果為意義不明的不典型鱗狀細胞(ASCUS)及以上的病例行陰道鏡下活檢病理組織學確診.結果 HPV檢測暘性61例,暘性率為6.09％,HPV型彆以HPV 16、58、18、6、51、52、66型為主.LCT結果為ASCUS及以上的病例28例,陰道鏡下活檢確診宮頸上皮內瘤變(CIN)Ⅰ 8例,CINⅡ2例,CINⅢ3例,宮頸早期浸潤癌1例.結論 ①深圳市囉湖社區已婚婦女中有6.09％存在HPV感染,HPV型彆以16、58、18、6、51、52、66型較為多見.②HPV聯閤LCT檢查及陰道鏡下活檢,能有效檢齣宮頸病變病例,這對宮頸上皮內瘤變及宮頸癌的早期診治具有重要臨床應用價值.
목적 료해심수시라호사구이혼육령부녀인유두류병독(HPV)감염적류행상황,탐토HPV검측재궁경병변사사중적림상응용개치.방법 응용다취합매련반응(PCR-MS) HPV분형검측방법,대1002례이혼부녀진행하생식도HPV형별검측,대기중양성병례행액기세포학검사(LCT)검사,대LCT결과위의의불명적불전형린상세포(ASCUS)급이상적병례행음도경하활검병리조직학학진.결과 HPV검측양성61례,양성솔위6.09％,HPV형별이HPV 16、58、18、6、51、52、66형위주.LCT결과위ASCUS급이상적병례28례,음도경하활검학진궁경상피내류변(CIN)Ⅰ 8례,CINⅡ2례,CINⅢ3례,궁경조기침윤암1례.결론 ①심수시라호사구이혼부녀중유6.09％존재HPV감염,HPV형별이16、58、18、6、51、52、66형교위다견.②HPV연합LCT검사급음도경하활검,능유효검출궁경병변병례,저대궁경상피내류변급궁경암적조기진치구유중요림상응용개치.
Objective To understand human papillomavirus(HPV)infection status in 1002 married women in Luohu community,in Shenzhen,and to investigate the value of HPV detection on screening of cervical lesions.Methods Polymerase chain reaction(PCR) HPV method was used to detect HPV type,the positive cases were examined by liquid-based cytology test (LCT).A biopsy under colposcopy was performed in women whose LCT test ≥ atypical squamous cells of determined significance(ASC-US).Results Sixty-one cases were positive in 1002 cases,the positive rate of HPV infection was 6.09％,HPV 16,58,18,6,51,52 and 66 type were more common.Women whose LCT results ≥ASC-US were 28 cases.Biopsy under colposcope diagnosis of cervical intraepithelial neoplasia(CIN) Ⅰ in 18 cases,CIN Ⅱ in9 cases,CIN Ⅲ in 3 cases,cervical cancer in 1 case.Conclusions About 6.09％ married women in Luohu community,in Shenzhen,have HPV infection,type 16,58,18,6,51,52 and 66 are more common.HPV combined with LCT and biopsy under colposcopy can effectively detect cervical lesions,that will has important clinical application value in early diagnosis and treatment of cervical intraepithelial neoplasia and cervical cancer.
