CAJ | 학술논문

目的分析血液降钙素原(PCT)、白细胞(WBC)、70％临界值中性粒细胞(NEU％)及C反应蛋白(CRP)在老年人败血症患者中的诊断价值.方法回顾性分析2013年1月至12月血培养阳性患者116例、阴性患者50例,对血液PCT、WBC、NEU％、CRP进行诊断评价.结果 PCT、WBC、70％临界值的NEU％及CRP在血培养阳性组和血培养阴性组的组间比较差异有统计学意义(P＜0.05).联合检测PCT、WBC及NEU％三项指标时,敏感度为82.4％,特异性为40.0％,阳性预测率为52.6％,阴性预测率为74.0％.单因素和多因素分析统计中,PCT、WBC及NEU％均可作为单独预测因素.结论 PCT、WBC及NEU％可作为早期诊断败血症的指标,在败血症早期具有诊断意义.
목적 분석혈액강개소원(PCT)、백세포(WBC)、70％림계치중성립세포(NEU％)급C반응단백(CRP)재노년인패혈증환자중적진단개치.방법 회고성분석2013년1월지12월혈배양양성환자116례、음성환자50례,대혈액PCT、WBC、NEU％、CRP진행진단평개.결과 PCT、WBC、70％림계치적NEU％급CRP재혈배양양성조화혈배양음성조적조간비교차이유통계학의의(P＜0.05).연합검측PCT、WBC급NEU％삼항지표시,민감도위82.4％,특이성위40.0％,양성예측솔위52.6％,음성예측솔위74.0％.단인소화다인소분석통계중,PCT、WBC급NEU％균가작위단독예측인소.결론 PCT、WBC급NEU％가작위조기진단패혈증적지표,재패혈증조기구유진단의의.
Objective To investigate the diagnostic values of procalcitonin (PCT),white blood cell (WBC) count,70％ marginal values of neutral granular cell (NEU％) and C reactive protein (CRP) to old patients with sepsis.Methods An analysis was conducted including both 116 sepsis patients with positive blood culture and 50 patients with negative blood culture from January to December in 2013.The serum PCT,WBC,NEU％ and CRP were tested.Results The levels of serum PCT,WBC,CRP and 70％ marginal values NEU％ in the positive blood culture group were significantly higher than those in the negative group (P ＜ 0.05).Combination of PCT,WBC and NEU％,the sensitivity,specificity,positive predictive value,and negative predictive value were 82.4％,40％,52.6％ and 74％ respectively.PCT,WBC and NEU％ might be considered respectively as single predictor through univariate and multivariate analysis in old patients with sepsis.Conclusion Serum PCT,WBC and NEU％ may be used as markers in early diagnosis of sepsis.The combined determination of serum PCT,WBC and NEU％ helps to exclude the diagnosis of sepsis.