国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2014年
22期
3357-3361
,共5页
居金金%徐飞华%魏宜胜%张畅%陆新容
居金金%徐飛華%魏宜勝%張暢%陸新容
거금금%서비화%위의성%장창%륙신용
胃癌%血红蛋白%血小板淋巴细胞比率%中性粒细胞淋巴细胞比率%吸烟%饮酒%护理
胃癌%血紅蛋白%血小闆淋巴細胞比率%中性粒細胞淋巴細胞比率%吸煙%飲酒%護理
위암%혈홍단백%혈소판림파세포비솔%중성립세포림파세포비솔%흡연%음주%호리
Gastric cancer%Hemoglobin%Platelet to lymphocyte ratio%Neutrophil to lymphocyte ratio%Smoking%Drinking%Nursing
目的 探讨吸烟饮酒对胃癌治疗前血红蛋白、血小板淋巴细胞比率(platelet to lymphocyte ratio,PLR)、中性粒细胞淋巴细胞比率(neutrophil to lymphocyte ratio,NLR)的影响.方法 纳入202例胃癌病例,单因素Kruskal-Wallis和多元线性回归分析吸烟、饮酒与胃癌治疗前血红蛋白、PLR、NLR的关系.结果 Kruskal-Wallis显示吸烟对胃癌治疗前血红蛋白、PLR、NLR差异有统计学意义(P=0.010,0.009,0026),饮酒则对胃癌治疗前血红蛋白、PLR、NLR无明显影响(P=0.415,0.090,0.168).多元线性回归显示吸烟对胃癌治疗前血红蛋白(P=0.001)、PLR(P=0.001)有显著关联,但对胃癌治疗前NLR无显著关联(P=0.246);饮酒对治疗前血红蛋白(P=0.930)、PLR(P=0.665)、NLR (P=0.817)无显著关联;吸烟(P=0.988)、饮酒(P=0.407)不是影响胃癌分期的独立影响因素.结论 吸烟是影响胃癌治疗前血红蛋白降低、PLR升高的独立危险因素,应加强护理干预,改善患者血红蛋白及全身性炎症反应.
目的 探討吸煙飲酒對胃癌治療前血紅蛋白、血小闆淋巴細胞比率(platelet to lymphocyte ratio,PLR)、中性粒細胞淋巴細胞比率(neutrophil to lymphocyte ratio,NLR)的影響.方法 納入202例胃癌病例,單因素Kruskal-Wallis和多元線性迴歸分析吸煙、飲酒與胃癌治療前血紅蛋白、PLR、NLR的關繫.結果 Kruskal-Wallis顯示吸煙對胃癌治療前血紅蛋白、PLR、NLR差異有統計學意義(P=0.010,0.009,0026),飲酒則對胃癌治療前血紅蛋白、PLR、NLR無明顯影響(P=0.415,0.090,0.168).多元線性迴歸顯示吸煙對胃癌治療前血紅蛋白(P=0.001)、PLR(P=0.001)有顯著關聯,但對胃癌治療前NLR無顯著關聯(P=0.246);飲酒對治療前血紅蛋白(P=0.930)、PLR(P=0.665)、NLR (P=0.817)無顯著關聯;吸煙(P=0.988)、飲酒(P=0.407)不是影響胃癌分期的獨立影響因素.結論 吸煙是影響胃癌治療前血紅蛋白降低、PLR升高的獨立危險因素,應加彊護理榦預,改善患者血紅蛋白及全身性炎癥反應.
목적 탐토흡연음주대위암치료전혈홍단백、혈소판림파세포비솔(platelet to lymphocyte ratio,PLR)、중성립세포림파세포비솔(neutrophil to lymphocyte ratio,NLR)적영향.방법 납입202례위암병례,단인소Kruskal-Wallis화다원선성회귀분석흡연、음주여위암치료전혈홍단백、PLR、NLR적관계.결과 Kruskal-Wallis현시흡연대위암치료전혈홍단백、PLR、NLR차이유통계학의의(P=0.010,0.009,0026),음주칙대위암치료전혈홍단백、PLR、NLR무명현영향(P=0.415,0.090,0.168).다원선성회귀현시흡연대위암치료전혈홍단백(P=0.001)、PLR(P=0.001)유현저관련,단대위암치료전NLR무현저관련(P=0.246);음주대치료전혈홍단백(P=0.930)、PLR(P=0.665)、NLR (P=0.817)무현저관련;흡연(P=0.988)、음주(P=0.407)불시영향위암분기적독립영향인소.결론 흡연시영향위암치료전혈홍단백강저、PLR승고적독립위험인소,응가강호리간예,개선환자혈홍단백급전신성염증반응.
Objective To investigate the impact of smoking and drinking on hemoglobin,PLR (platelet to lymphocyte ratio),NLR (neutrophil to lymphocyte ratio) in patients with gastric cancer before treatment.Method The relationship between smoking,drinking and hemoglobin,PLR,NLR in 202 patients with gastric cancer before treatment was analyzed by single factor Kruskal-Wallis and multivariate linear regression analysis.Results Kruskal-Wallis showed smoking had a significant effect on pretreatment hemoglobin,PLR,NLR (P=0.010,0.009,0.026),while drinking had no significant effect on pretreatment hemoglobin,PLR,NLR (P=0.415,0.090,0.168).Multivariate linear regression analysis showed there were significant correlations between smoking and pretreatment hemoglobin,PLR (P=0.001,0.001),while no significant correlation between smoking and NLR (P=0.246); there were no significant correlations between drinking and pretreatment hemoglobin,PLR,NLR (P=0.930,0.665,0.817).Smoking and drinking were not independent risk factors for the stage of gastric cancer (P=0.988,0.407).Conclusions Smoking is a independent risk factor for pretreatment hemoglobin decreasing and pretreatment PLR increasing in patients with gastric cancer.Nursing intervention should be reinforced to improve hemoglobin and systemic inflammatory response in patients with gastric cancer.
