国际病毒学杂志
國際病毒學雜誌
국제병독학잡지
INTERNATIONAL JOURNAL OF VIROLOGY
2013年
4期
187-189
,共3页
彩色多普勒超声%抗病毒治疗%慢性丙型肝炎%评价%疗效
綵色多普勒超聲%抗病毒治療%慢性丙型肝炎%評價%療效
채색다보륵초성%항병독치료%만성병형간염%평개%료효
Color doppler ultrasound%Antiviral therapy%Chronic hepatitis C%Evaluation%Curative effect
目的 应用彩色多普勒超声评价慢性丙型肝炎患者抗病毒治疗的效果.方法 以2011年4月至2013年4月到四川省双流县第二人民医院就诊的45例慢性丙型肝炎患者作为研究对象,全部患者采用抗病毒治疗12w,根据治疗后病毒RNA表达情况判定疗效,并用彩色多普勒超声对治疗效果进行多维度评价.结果 患者经抗病毒治疗后,20例治疗有疗,25例无效.通过彩色多普勒超声检测发现,20例治疗有效的患者皆出现脾脏SI值(spleen index,脾指数)值下降、ALT值(glutamic-pyruvic transaminase,谷丙转氨酶)值减小及血小板值上升.在25例治疗无效的患者中,脾脏SI值下降的患者有11例(44.0％)；ALT值减小的患者9例(36.0％)；血小板值上升患者10例(40.0％).两组患者在抗病毒治疗前后,脾脏SI值、ALT值及血小板值三个指标的检测结果差异均有统计学意义(P＜0.05).结论 慢性丙型肝炎患者采用抗病毒治疗可取得较好的疗效,应用彩色多普勒超声技术可从多维度对慢性丙型肝炎的疗效进行评价.
目的 應用綵色多普勒超聲評價慢性丙型肝炎患者抗病毒治療的效果.方法 以2011年4月至2013年4月到四川省雙流縣第二人民醫院就診的45例慢性丙型肝炎患者作為研究對象,全部患者採用抗病毒治療12w,根據治療後病毒RNA錶達情況判定療效,併用綵色多普勒超聲對治療效果進行多維度評價.結果 患者經抗病毒治療後,20例治療有療,25例無效.通過綵色多普勒超聲檢測髮現,20例治療有效的患者皆齣現脾髒SI值(spleen index,脾指數)值下降、ALT值(glutamic-pyruvic transaminase,穀丙轉氨酶)值減小及血小闆值上升.在25例治療無效的患者中,脾髒SI值下降的患者有11例(44.0％)；ALT值減小的患者9例(36.0％)；血小闆值上升患者10例(40.0％).兩組患者在抗病毒治療前後,脾髒SI值、ALT值及血小闆值三箇指標的檢測結果差異均有統計學意義(P＜0.05).結論 慢性丙型肝炎患者採用抗病毒治療可取得較好的療效,應用綵色多普勒超聲技術可從多維度對慢性丙型肝炎的療效進行評價.
목적 응용채색다보륵초성평개만성병형간염환자항병독치료적효과.방법 이2011년4월지2013년4월도사천성쌍류현제이인민의원취진적45례만성병형간염환자작위연구대상,전부환자채용항병독치료12w,근거치료후병독RNA표체정황판정료효,병용채색다보륵초성대치료효과진행다유도평개.결과 환자경항병독치료후,20례치료유료,25례무효.통과채색다보륵초성검측발현,20례치료유효적환자개출현비장SI치(spleen index,비지수)치하강、ALT치(glutamic-pyruvic transaminase,곡병전안매)치감소급혈소판치상승.재25례치료무효적환자중,비장SI치하강적환자유11례(44.0％)；ALT치감소적환자9례(36.0％)；혈소판치상승환자10례(40.0％).량조환자재항병독치료전후,비장SI치、ALT치급혈소판치삼개지표적검측결과차이균유통계학의의(P＜0.05).결론 만성병형간염환자채용항병독치료가취득교호적료효,응용채색다보륵초성기술가종다유도대만성병형간염적료효진행평개.
Objective Using color doppler ultrasound to evaluate the curative effect of antiviral treatment to chronic hepatitis C.Methods A total of 45 cases who visited the Second People's Hospital of Shuangliu from April 2011 to April 2013 were collected in our study.All the patients were treated with antiviral treatment.CHC-RNA testing was used to judge the effectiveness.Color doppler ultrasound was used to exam related indexes and to evaluate the curative effect from multi-dimensional.Results Being treated for 12 weeks,20 patients showed an effective result while 25 were judged as invalid by CHC-RNA testing.Being examined by color doppler ultrasound,cases who were judged as effectiveness showed a significant improve in indexes of spleen SI,ALT and platelet (P ＜ 0.05).Among the 25 cases who were judged as invalid,the spleen SI value decreased in 11 of them (44.0％) ; ALT value decreased in 9 (36.0％) ; 10 (40.0％) cases showed an increased platelet value.The indexes of SI,ALT and platelet have changed a lot after treatment both in effective group and ineffective group,the difference was significant (P ＜ 0.05).Conclusions Antiviral treatment is useful in treating patients with chronic hepatitis C.Color doppler ultrasonography could be used in evaluating the effectiveness chronic hepatitis C treatment from multi-dimensional.
