CAJ | 학술논문

目的分析急性呼吸道感染病例的病毒病原构成,掌握主要病原体活动水平及变化规律,了解丰台地区急性呼吸道感染病原谱.方法以2010-2012年成人急性呼吸道感染病例为研究对象,收集病例基础信息,采集鼻咽拭子标本,使用多重PCR及RT-PCR对流感病毒、呼吸道合胞病毒、腺病毒、副流感病毒、偏肺病毒、冠状病毒、鼻病毒、博卡病毒和肺炎支原体等9种病原进行检测,数据分析使用SPSS 17.0软件.结果 254例标本中154例检测阳性,阳性率为60.63％,男女阳性检出率无统计学差异.冬春季致病病原体以流感病毒、副流感病毒及支原体为主,夏季仅检出副流感和支原体.流感样病例的主要病原体为流感病毒及副流感病毒;肺炎病例致病病原体主要为肺炎支原体.2010-2011年流感流行季甲型流感病毒为优势病原,2011-2012年流感流行季乙型流感病毒为优势病原.结论 2010-2012年间,北京丰台地区引起成人急性呼吸道感染的主要病原为流感病毒、支原体和副流感病毒.不同季节的优势病原不同.
목적 분석급성호흡도감염병례적병독병원구성,장악주요병원체활동수평급변화규률,료해봉태지구급성호흡도감염병원보.방법 이2010-2012년성인급성호흡도감염병례위연구대상,수집병례기출신식,채집비인식자표본,사용다중PCR급RT-PCR대류감병독、호흡도합포병독、선병독、부류감병독、편폐병독、관상병독、비병독、박잡병독화폐염지원체등9충병원진행검측,수거분석사용SPSS 17.0연건.결과 254례표본중154례검측양성,양성솔위60.63％,남녀양성검출솔무통계학차이.동춘계치병병원체이류감병독、부류감병독급지원체위주,하계부검출부류감화지원체.류감양병례적주요병원체위류감병독급부류감병독;폐염병례치병병원체주요위폐염지원체.2010-2011년류감류행계갑형류감병독위우세병원,2011-2012년류감류행계을형류감병독위우세병원.결론 2010-2012년간,북경봉태지구인기성인급성호흡도감염적주요병원위류감병독、지원체화부류감병독.불동계절적우세병원불동.
Objective To analyze the viral etiology of acute respiratow infection,and to study the activity and epidemiological characteristic of main pathogens,so as to establish pathogen spectrum of acute respiratory infection in Fengtai district of Beijing.Methods Basic information and throat swabs of acute respiratory infection cases during 2010-2012 were collected.Influenza virus,respiratory syncytial virus,adenovirus,parainfluenza virus,metapneumovirus,coronavirus,rhinovirus,human Boca virus and mycoplasma pneumonia were detected by multiplex PCR and RT-PCR.SPSS 17.0 was used for data analysis.Results 154 were positive in all of the 254 samples,the positive ratio was 60.63％.Influenza viruses,parainfluenza virus and mycoplasma pneumoniae were the most frequently detected pathogens in winter and spring.Parainfluenza and mycoplasma were the only detected pathogens in summer.There was no significant difference in positive rate between male and female patients.Influenza viruses and parainfluenza virus were the major viral pathogens of influenza-like illness,mycoplasma pneumoniae was the major pathogen of pneumonia patients.Influenza A was dominate during 2010-2011,while influenza B as the major one during the 2011-2012 influenza season.Conclusions Influenza virus,mycoplasma pneumoniae,and parainfluenza virus were the main pathogens leading to acute respiratory infection during 2010-2012 in Fengtai district of Beijing.The major pathogens were different in different seasons.