国际儿科学杂志
國際兒科學雜誌
국제인과학잡지
INTERNATIONAL JOURNAL OF PEDIATRICS
2013年
6期
642-645
,共4页
哮喘%儿童%呼气相气道内负压法%呼气流速受限%第一秒用力呼气容积
哮喘%兒童%呼氣相氣道內負壓法%呼氣流速受限%第一秒用力呼氣容積
효천%인동%호기상기도내부압법%호기류속수한%제일초용력호기용적
Asthma%Children%Negative expiratory pressure(NEP)%Expiratory flow limitation(EFL)%Forced expiratory volume in first second
目的 探讨呼气相气道内负压法(NEP)检测呼气流速受限(EFL)在儿童哮喘患者中实施的可行性,及其与常规阻塞性肺通气功能指标第一秒用力呼气容积(FEV1)、加拿大医学研究委员会推荐的呼吸困难严重程度分级标准(MRC评分)的相关性.方法 选取2012年6～12月在该院就诊的儿童哮喘患者64例,其中46例稳定期,18例急性发作,给予MRC评分,然后分别进行常规肺通气功能检测及NEP检测EFL.结果 (1)所有哮喘患儿均能很好耐受NEP.(2)肺通气功能情况:64例哮喘患儿的FEV1均值为(71.33±13.92)％ pred,18例急性发作患儿FEV1均值为(52.91±13.87)％ pred.(3)MRC评分:64例哮喘患儿中10例MRC评分为2分,其余54例MRC评分为1分.MRC与FEV1的相关系数是-0.635(P＜0.05).(4)NEP检测EFL情况:46例哮喘患儿坐位和仰卧位均未出现EFL,8例坐位和仰卧位均有EFL,10例坐位时无EFL,仅仰卧位出现EFL.3分法EFL与FEV1及MRC的相关系数分别为-0.607、0.964(P ＜0.05).5分法EFL与FEV1及MRC的相关系数分别为-0.626、0.966(P＜0.05).结论 (1)NEP可用于检测儿童哮喘的EFL情况.(2)NEP检测EFL与FEV1显著相关.(3)NEP检测EFL指标和FEV1均与MRC评分显著相关,但EFL与MRC评分的相关性更强.
目的 探討呼氣相氣道內負壓法(NEP)檢測呼氣流速受限(EFL)在兒童哮喘患者中實施的可行性,及其與常規阻塞性肺通氣功能指標第一秒用力呼氣容積(FEV1)、加拿大醫學研究委員會推薦的呼吸睏難嚴重程度分級標準(MRC評分)的相關性.方法 選取2012年6～12月在該院就診的兒童哮喘患者64例,其中46例穩定期,18例急性髮作,給予MRC評分,然後分彆進行常規肺通氣功能檢測及NEP檢測EFL.結果 (1)所有哮喘患兒均能很好耐受NEP.(2)肺通氣功能情況:64例哮喘患兒的FEV1均值為(71.33±13.92)％ pred,18例急性髮作患兒FEV1均值為(52.91±13.87)％ pred.(3)MRC評分:64例哮喘患兒中10例MRC評分為2分,其餘54例MRC評分為1分.MRC與FEV1的相關繫數是-0.635(P＜0.05).(4)NEP檢測EFL情況:46例哮喘患兒坐位和仰臥位均未齣現EFL,8例坐位和仰臥位均有EFL,10例坐位時無EFL,僅仰臥位齣現EFL.3分法EFL與FEV1及MRC的相關繫數分彆為-0.607、0.964(P ＜0.05).5分法EFL與FEV1及MRC的相關繫數分彆為-0.626、0.966(P＜0.05).結論 (1)NEP可用于檢測兒童哮喘的EFL情況.(2)NEP檢測EFL與FEV1顯著相關.(3)NEP檢測EFL指標和FEV1均與MRC評分顯著相關,但EFL與MRC評分的相關性更彊.
목적 탐토호기상기도내부압법(NEP)검측호기류속수한(EFL)재인동효천환자중실시적가행성,급기여상규조새성폐통기공능지표제일초용력호기용적(FEV1)、가나대의학연구위원회추천적호흡곤난엄중정도분급표준(MRC평분)적상관성.방법 선취2012년6～12월재해원취진적인동효천환자64례,기중46례은정기,18례급성발작,급여MRC평분,연후분별진행상규폐통기공능검측급NEP검측EFL.결과 (1)소유효천환인균능흔호내수NEP.(2)폐통기공능정황:64례효천환인적FEV1균치위(71.33±13.92)％ pred,18례급성발작환인FEV1균치위(52.91±13.87)％ pred.(3)MRC평분:64례효천환인중10례MRC평분위2분,기여54례MRC평분위1분.MRC여FEV1적상관계수시-0.635(P＜0.05).(4)NEP검측EFL정황:46례효천환인좌위화앙와위균미출현EFL,8례좌위화앙와위균유EFL,10례좌위시무EFL,부앙와위출현EFL.3분법EFL여FEV1급MRC적상관계수분별위-0.607、0.964(P ＜0.05).5분법EFL여FEV1급MRC적상관계수분별위-0.626、0.966(P＜0.05).결론 (1)NEP가용우검측인동효천적EFL정황.(2)NEP검측EFL여FEV1현저상관.(3)NEP검측EFL지표화FEV1균여MRC평분현저상관,단EFL여MRC평분적상관성경강.
Objective The purpose of this study was to evaluate the feasibility of expiratory flow limitation(EFL) detected by negative(NEP) and the correlation between EFL and routine lung function measurements(Forced expiratory volume in first second,FEV1),EFL and MRC dyspnea scale,in patients with stable and acute asthma,to find a simple,reliable and objective method for the diagnosis,differential diagnosis,the severity of disease and evaluation of severity and efficacy of treatment for asthma,and a objective method reflecting the severity of dyspnea.Methods Sixty-four children enrolled in No.306 Hospital of PLA from Jun.to Dec.in 2012 were included in this study.The severity of dyspnea was rated according to the dyspnea scale proposed by the Medical Research Council(MRC).Then routine pulmonary ventilation function tests and NEP technique were performed respectively.Result (1) All asthmatic patients tolerated NEP well.(2) Pulmonary ventilation function tests:The mean FEV1 in 64 was 71.33 ± 13.92％ pred.(3) MRC dyspnea scale:MRC dyspnea scale was 2 in 10,1 in 54 of 64 children with stable asthma.The Spearman' s correlation coefficient of MRC dyspnea scale with FEV1 was-0.635(P ＜0.05).(4)EFL detected by NEP:There were no EFL in 46 children with asthma both in seated and supine positions.There were EFL in 8 children both in seated and supine positions and in 10 only in supine position..The Spearman's correlation coefficient of three-point EFL score with FEV1 and MRC dyspnea scale was-0.607 and 0.964(P ＜ 0.05) respectively.The Spearman's correlation coefficient of five-point EFL score with FEV1 and MRC dyspnea scale was-0.626 and 0.966 (P ＜ 0.05)respectively.Conclusion (1) NEP technique can be used in children with asthma.(2) There was a significant correlation between EFL detected by NEP technique and FEV1.(3) There is a stronger correlation between EFL and MRC dyspnea scale than that between FEV1 and MRC dyspnea scale.
